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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 798 - 804 (7page)
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Purpose: This study aimed to compare the regulatory T cells in cord blood of appropriatefor gestational age (AGA) neonates with those of small for gestational age (SGA) neonates. Materials and Methods: Umbilical cord blood was collectedupon labor in 108 healthy full-term (between 37 and 41 gestational weeks) neonates, who were born between November 2010 and April 2012. Among them, 77 samples were obtained from AGA neonates, and 31 samples were obtained from SGA neonates. Regulatory T cells and lymphocyte subsets were determined using a flow cytometer. Student’s t-test for independent samples was used to comparedifferences between AGA and SGA neonates. Results: Regulatory T cells in cord blood were increased in the SGA group compared with normal controls (p=0.041). However, cytotoxic T cells in cord blood were significantly decreased in the SGA group compared with normal controls (p=0.007). Conclusion: This is the first study to compare the distribution of lymphocyte subsets including regulatoryT cells in cord blood between AGA neonates and SGA neonates.
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등록된 정보가 없습니다.
참고문헌 (43)
참고문헌 신청
Sasaki Y / 2004 / Decidual and peripheral blood CD4+CD25+ regulatory T cells in early pregnancy subjects and spontaneous abortion cases / Mol Hum Reprod 10:347~353
Aluvihare VR / 2004 / Regulatory T cells mediate maternal tolerance to the fetus / Nat Immunol 5:266~271
King A / 1991 / On the nature and function of human uterine granular lymphocytes / Immunol Today 12:432~435
Stallmach T / 1995 / Cytokine production and visualized effects in the feto-maternal unit. Quantitative and topographic data on cytokines during intrauterine disease / Lab Invest 73:384~392
Jasper MJ / 2006 / Primary unexplained infertility is associated with reduced expression of the T-regulatory cell transcription factor Foxp3 in endometrial tissue / Mol Hum Reprod 12:301~308
Aluvihare VR / 2004 / Regulatory T cells mediate maternal tolerance to the fetus / Nat Immunol 5:266~271
King A / 1991 / On the nature and function of human uterine granular lymphocytes / Immunol Today 12:432~435
Stallmach T / 1995 / Cytokine production and visualized effects in the feto-maternal unit. Quantitative and topographic data on cytokines during intrauterine disease / Lab Invest 73:384~392
Jasper MJ / 2006 / Primary unexplained infertility is associated with reduced expression of the T-regulatory cell transcription factor Foxp3 in endometrial tissue / Mol Hum Reprod 12:301~308
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