지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2008.1
- 수록면
- 532 - 536 (5page)
이용수
초록· 키워드
오류제보하기
Purpose: This study was designed to evaluate effect of EMD on proliferation of HPDLCs and MC3T3-E1 cells in high glucose condition in vitro.
Material and method: The Human PDL fibroblasts(HPDLCs) were obtained through typical way and the cells used in this experiment were divided in 4 groups. 1x104/ml HPDLCs suspension was cultured in typical DMEM and assigned to group 1. The cells cultured in DMEM which included 400mg/dl glucose are allocated to group 3. Group 2 and 4 are established by adding EMD to group 1 and 3 respectively. These control and experimental groups had been cultured for 24 and 48 hours, and MTT assay was conducted. The differences of each group in cellular proliferation was evaluated. The same experiment was conducted for preosteoblast (MC3T3-E1) with adding 25㎍/ml EMD.
Results: EMD had the same effect on both PDL cells and MCT3T3-E1 cells. The experimental group had more meaningful differences and active cellular proliferation than the control group did. The EMD accelerated cellular proliferation not only in normal glucose condition but also in high glucose condition. The same results were observed via MTT assay; EMD-added experimental group had more meaningful differences and showed higher cellular activity than control group did. Each experimental and control group was inspected for statistical significance through Kruskal-Wallis Test. Statistical significances were observed among these groups. (SPSS 12.0 Chicago, IL, USA, p=0.008, p=0.011)
Conclusion: EMD is considered to accelerate proliferation of PDL cells and MC3T3-E1 cells in high glucose condition as well as normal glucose condition.
목차
등록된 정보가 없습니다.
참고문헌 (25)
참고문헌 신청
Beertsen W / 2000 / The periodontal ligament: a unique, multifunctional connective tissue / J. Periodontol 13 : 20 ~ 40
Glavind L / 1969 / The relationship between periodontal state and diabetes duration, insulin dosage and retinal changes / J. Perio. Res 4 : 164 ~ 165
Hammarstrom L / 1997 / Periodontal regeneration in a buccal dehiscence model in monkeys after application of enamel matrix proteins / J. Clin. Periodontol 24 : 669 ~ 677
Heden G / 1999 / Periodontal tissue alterations following Emdogain treatment of periodontal sites with angular bone defects. A series of case reports / J. Clin. Periodontol
Hehenberger K /
Glavind L / 1969 / The relationship between periodontal state and diabetes duration, insulin dosage and retinal changes / J. Perio. Res 4 : 164 ~ 165
Hammarstrom L / 1997 / Periodontal regeneration in a buccal dehiscence model in monkeys after application of enamel matrix proteins / J. Clin. Periodontol 24 : 669 ~ 677
Heden G / 1999 / Periodontal tissue alterations following Emdogain treatment of periodontal sites with angular bone defects. A series of case reports / J. Clin. Periodontol
Hehenberger K /
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
법랑기질유도체가 탈회 치근표면에서 치주인대섬유아세포의 생물학적 성상에 미치는 영향
Journal of Periodontal & Implant Science
2008 .01
-
Cellular viability and genetic expression of human gingival fibroblasts to zirconia with enamel matrix derivative (Emdogain®)
The Journal of Advanced of Prosthodontics
2014 .01
-
Enamel Matrix Derivatives가 사람 치주인대 세포의 특이유전자인 PDLs17, PDLs22의 발현에 끼치는 효과
Journal of Periodontal & Implant Science
2004 .01
-
Enamel matrix derivative for replanted teeth in animal models: a systematic review and meta-analysis
Restorative Dentistry and Endodontics
2013 .01
-
골내 결손부에서 법랑기질 유도체의 임상적 효과
Journal of Periodontal & Implant Science
2004 .01
-
역위 매복된 상악 소구치의 Enamel matrix derivative를 이용한 자가이식 치험례
대한소아치과학회지
2003 .01
-
글라스-아이오노머 시멘트와 Emdogain®을 이용한 구개치은발육구의 치료
대한치과의사협회지
2010 .01
-
Regulation of bone formation by high glucose in PDL cells
한국응용약물학회 추계학술발표논문집
2003 .01
-
Alveolar ridge preservation following extraction of multiple anterior teeth with and without adjunctive enamel matrix derivative: A case report
Oral Biology Research
2019 .01
-
플라즈마 표면처리 조건에 따른 MC3T3-E1 세포 증식에 관한 연구
대한치과재료학회 학술대회
2010 .04
-
Microbiological and clinical effects of enamel matrix derivative and sustained-release micro-spherical minocycline application as an adjunct to non-surgical therapy in peri-implant mucosal inf ammation
대한구강악안면외과학회지
2015 .01
-
법랑기질유도체가 인간 치주인대세포의 증식 및 성장인자 발현에 미치는 영향
대한치과보철학회지
2016 .01
-
각종 홀몬이 체외배양 골아세포(MC3T3 cell)에 미치는 영향에 관한 연구
대한정형외과학회지
1989 .06
-
Differentiation and characteristics of undifferentiated mesenchymal stem cells originating from adult premolar periodontal ligaments
대한치과교정학회지
2012 .12
-
Effects of High Glucose Levels on the Protein Kinase C Signal Transduction Pathway in Primary Cultured Renal Proximal Tubule Cells
대한생리학회지
1996 .01
-
High Glucose Inhibitory Effects on Bone Formation in UMR106 Cells
The journal of applied pharmacology : the official journal of the Korean Society of Applied Pharmacology
2003 .01
-
Effect of High glucose on JNK/ERK signaling pathway in UMR106 cells
한국응용약물학회 추계학술발표논문집
2003 .01
-
Effect of Extracellular Glucose on the Proliferation and Extracellular Matrix Synthesis of the Cultured Osteoblasts and Periodontal Ligament Cells
대한체질인류학회 학술대회 연제 초록
2008 .05
-
홍화씨 추출물이 MC3T3-E1 조골세포의 증식과 분화에 미치는 영향
Oral Biology Research
2013 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0