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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한치주과학회 Journal of Periodontal & Implant Science Journal of Periodontal & Implant Science 제38권 제4호
- 발행연도
- 2008.1
- 수록면
- 679 - 690 (12page)
이용수
초록· 키워드
오류제보하기
Purpose: The aim of this study was to investigate the effects of EMD on demineralized root surface using human periodontal ligament cells and compare the effects of root conditioning materials(tetracycline(TCN), EDTA).
Material and Methods: Dentin slices were prepared from the extracted teeth and demineralized with TCN and EDTA. Demineralized dentin slices were incubated at culture plate with 25, 50 and 100 ㎍/ml concentration of EMD. Cell attachment, alkaline phosphatase activity test, protein synthesis assay and scanning electronic microscopic examination were done.
Results: Cells were attached significantly higher in EMD treated group at 7 and 14 days. Cell numbers were significantly higher in EMD treated group.
Alkaline phosphatase activity was significantly higher in EMD treated group at 7 and 14 days. Protein synthesis was significantly higher in EMD treated group at 7 and 14 days.
Conclusion: Enamel matrix derivatives enhance the biologic activities of human periodontal ligament cells on demineralized root surface and its effects are dependent on the concentration of EMD. (J Korean Acad Periodontol 2008;38:679-690)
목차
등록된 정보가 없습니다.
참고문헌 (22)
참고문헌 신청
/ 2004 / Behavior of human periodontal ligament cells on CO2 laser irradiated dentinal root surfaces: an in vitro study / J Periodon Res 39 : 373 ~ 379
Cattaneo V / 2003 / Effect of enamel matrix derivative on human periodontal fibroblast: proliferation, morphology and root surface colonization. An in vitro study / J Period
Chano L / 2003 / Emdogain regulation of cellular differentiation in wounded rat periodontium / J Periodontal Res 38 : 164 ~ 174
Chong CH / 2006 / Human periodontal fibroblast response to enamel matrix derivative, amelogenin, and platelet-derived growth factor-BB / J Periodontol 77 : 1242 ~ 1252
Davenport DR / 2003 / Effects of enamel matrix protein application on the viability, proliferation, and attachment of human periodontal ligament fibroblasts to diseased root
Cattaneo V / 2003 / Effect of enamel matrix derivative on human periodontal fibroblast: proliferation, morphology and root surface colonization. An in vitro study / J Period
Chano L / 2003 / Emdogain regulation of cellular differentiation in wounded rat periodontium / J Periodontal Res 38 : 164 ~ 174
Chong CH / 2006 / Human periodontal fibroblast response to enamel matrix derivative, amelogenin, and platelet-derived growth factor-BB / J Periodontol 77 : 1242 ~ 1252
Davenport DR / 2003 / Effects of enamel matrix protein application on the viability, proliferation, and attachment of human periodontal ligament fibroblasts to diseased root
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