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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국미생물생명공학회 Journal of Microbiology and Biotechnology Journal of Microbiology and Biotechnology 제28권 제1호
- 발행연도
- 2018.1
- 수록면
- 22 - 31 (10page)
이용수
초록· 키워드
오류제보하기
Isoflavone itself is less available in the body without the aid of intestinal bacteria. In this study, we searched for isoflavone-transforming bacteria from human fecal specimens (n = 14) using differential selection media. Isoflavone-transforming activity as the production of dihydrogenistein and dihydrodaidzein was assessed by high-performance liquid chromatography and we found Lactobacillus rhamnosus, named L. rhamnosus vitaP1, through 16S rDNA sequence analysis. Extract from Pueraria lobata (EPL) and soy hypocotyl extract were fermented with L. rhamnosus vitaP1 for 24 and 48 h at 37oC. Fermented EPL (FEPL) showed enhanced anti-tyrosinase activity and antioxidant capacities, important suppressors of the pigmentation process, compared with that of EPL (p < 0.05). At up to 500 μg/ml of FEPL, there were no significant cell cytotoxicity and proliferation on B16-F10 melanoma cells. FEPL (100 μg/ml) could highly suppress the content of melanin and melanosome formation in B16- F10 cells. In summary, Lactobacillus rhamnosus vitaP1 was found to be able to biotransform isoflavones in EPL. FEPL showed augmented anti-melanogenic potential.
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등록된 정보가 없습니다.
참고문헌 (28)
참고문헌 신청
Kim DY / 2015 / Potential skin regeneration activity and chemical composition of absolute from Pueraria thunbergiana flower / Nat. Prod. Commun. 10:2009~2012
Park EK / 2006 / Intestinal bacteria activate estrogenic effect of main constituents puerarin and daidzin of Pueraria thunbergiana / Biol. Pharm. Bull. 29:2432~2435
Woo J / 2003 / Comparison of Pueraria lobata with hormone replacement therapy in treating the adverse health consequences of menopause / Menopause 10:352~361
Han E / 2015 / Melanogenesis inhibitory effect of aerial part of Pueraria thunbergiana in vitro and in vivo / Arch. Dermatol. Res. 307:57~72
Pham AK / 2014 / Cosmeceuticals for children: should you care? / Curr. Opin. Pediatr. 26:446~451
Park EK / 2006 / Intestinal bacteria activate estrogenic effect of main constituents puerarin and daidzin of Pueraria thunbergiana / Biol. Pharm. Bull. 29:2432~2435
Woo J / 2003 / Comparison of Pueraria lobata with hormone replacement therapy in treating the adverse health consequences of menopause / Menopause 10:352~361
Han E / 2015 / Melanogenesis inhibitory effect of aerial part of Pueraria thunbergiana in vitro and in vivo / Arch. Dermatol. Res. 307:57~72
Pham AK / 2014 / Cosmeceuticals for children: should you care? / Curr. Opin. Pediatr. 26:446~451
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