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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국미생물생명공학회 Journal of Microbiology and Biotechnology Journal of Microbiology and Biotechnology 제19권 제2호
- 발행연도
- 2009.1
- 수록면
- 204 - 207 (4page)
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초록· 키워드
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We investigated novel antibacterial and synergistic activities
of isocryptomerin isolated from Selaginella tamariscina.
Isocryptomerin showed potent antibacterial activity against
Gram-positive and Gram-negative bacterial strains including
clinical isolates of antibiotic-resistant species such as methicillinresistant
Staphylococcus aureus (MRSA). Additionally, we
further investigated the synergistic activity of isocryptomerin
with a conventional antibiotic against MRSA. The result
indicated that isocryptomerin had considerable synergistic
activity in combination with cefotaxime. In summary, the
present study suggests that isocryptomerin may have potential
as a novel therapeutic agent for treatment of infectious
diseases by not only human pathogenic bacteria but also
multidrug-resistant bacteria.
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참고문헌 (22)
참고문헌 신청
Bauer, R. / 2005 / Mode of action of lipid IItargeting lantibiotics / Int. J. Food Microbiol 101 : 201 ~ 216
Bush, K. / 2004 / Antibacterial drug discovery in the 21st century / Clin. Microbiol. Infect 10 (4) : 10 ~ 17
Cassell, G. H. / 1997 / Emergent antibiotic resistance: Health risks and economic impact / FEMS Immunol. Med. Microbiol 18 : 271 ~ 274
Cavalieri, S. J. / 1995 / Synergistic activities of clarithromycin and antituberculous drugs against multidrug-resistant Mycobacterium tuberculosis / Antimicrob. Agents Chemo
Cha, D. S. / 2004 / Biopolymer-based antimicrobial packaging: A review / Crit. Rev. Food Sci. Nutr 44 : 223 ~ 237
Bush, K. / 2004 / Antibacterial drug discovery in the 21st century / Clin. Microbiol. Infect 10 (4) : 10 ~ 17
Cassell, G. H. / 1997 / Emergent antibiotic resistance: Health risks and economic impact / FEMS Immunol. Med. Microbiol 18 : 271 ~ 274
Cavalieri, S. J. / 1995 / Synergistic activities of clarithromycin and antituberculous drugs against multidrug-resistant Mycobacterium tuberculosis / Antimicrob. Agents Chemo
Cha, D. S. / 2004 / Biopolymer-based antimicrobial packaging: A review / Crit. Rev. Food Sci. Nutr 44 : 223 ~ 237
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