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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국미생물생명공학회 Journal of Microbiology and Biotechnology Journal of Microbiology and Biotechnology 제18권 제3호
- 발행연도
- 2008.1
- 수록면
- 472 - 476 (5page)
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Two isoforms of human CD99 have been identified, but only
heterotypic interaction between the isomers was recently
demonstrated. In this study, we performed bimolecular
fluorescence complementation analysis to further characterize
the interaction in vivo. Upon transiently transfecting
plasmids expressing either of the two isoforms fused with
yellow fluorescent protein (YFP) fragments, all the YFPtagged
CD99 molecules were properly localized on cell
surfaces, and formed fluorescent dimers. Interestingly,
however, unlike the previous report, the homodimers formed
as efficiently as the heterodimer via their extracellular
domains, implying its distinct regulatory role through
modulating the complex profile.
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참고문헌 (21)
참고문헌 신청
Alberti, I. / 2002 / CD99 isoforms expression dictates T cell functional outcomes / FASEB 16 : 1946 ~ 1948
Aubrit, F. / 1989 / The biochemical characterization of E2, a T cell surface molecule involved in rosettes. Eur / Immunol 19 : 1431 ~ 1436
Bernard, G. / 1997 / Apoptosis of immature thymocytes mediated by E2/CD99 / Immunol 158 : 2543 ~ 2550
Byun, H. J. / 2006 / A splicevariant of CD99 increases motility and MMP-9 expression of human breast cancer cells through the AKT-, ERK-, and JNKdependent AP-1 activation sig
Choi, E. Y. / 1998 / Engagement of CD99 induces up-regulation of TCR and MHC class I and II molecules on the surface of human thymocytes. J / Immunol 161 : 749 ~ 754
Aubrit, F. / 1989 / The biochemical characterization of E2, a T cell surface molecule involved in rosettes. Eur / Immunol 19 : 1431 ~ 1436
Bernard, G. / 1997 / Apoptosis of immature thymocytes mediated by E2/CD99 / Immunol 158 : 2543 ~ 2550
Byun, H. J. / 2006 / A splicevariant of CD99 increases motility and MMP-9 expression of human breast cancer cells through the AKT-, ERK-, and JNKdependent AP-1 activation sig
Choi, E. Y. / 1998 / Engagement of CD99 induces up-regulation of TCR and MHC class I and II molecules on the surface of human thymocytes. J / Immunol 161 : 749 ~ 754
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