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- 한국미생물생명공학회 Journal of Microbiology and Biotechnology Journal of Microbiology and Biotechnology 제19권 제11호
- 발행연도
- 2009.1
- 수록면
- 1,319 - 1,327 (9page)
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Marine red algae of genus Laurencia are becoming themost important resources to produce unique naturalmetabolites with wide bioactivities. However, reports relatedto Laurencia undulata, an edible species used as folk herb,are rarely found to date. In this research, 5-hydroxymethyl-2-furfural (5-HMF) was isolated and characterized bynuclear magnetic resonance (NMR) from Laurencia undulataas well as other marine algae. The following characteristicsof 5-HMF were systematically evaluated: its antioxidantactivities, such as typical free-radicals scavenging in vitro byelectron spin resonance spectrometry (ESR) and intracellularreactive oxygen species (ROS) scavenging; membraneprotein oxidation; oxidative enzyme myeloperoxidase (MPO)inhibition; as well as expressions of antioxidative enzymesglutathione (GSH) and superoxide dismutase (SOD) onthe gene level using the polymerase chain reaction (PCR)method. The results demonstrated that 5-HMF could bedeveloped as a novel marine natural antioxidant or potentialprecursor for practical applications in the food, cosmetic,and pharmaceutical fields.
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참고문헌 (24)
참고문헌 신청
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Antolovich, M. / 2002 / Methods for testing antioxidant activity / Analyst 127 : 183 ~ 198
Baik, Jong Seok / 2008 / Chemical Composition and Biological Activities of Essential Oils Extractedfrom Korean Endemic Citrus Species / Journal of Microbiology and Biotechnol
Beckman, J. S. / 1990 / Apparent hydroxyl radical production by peroxynitrite: Implications for endothelial injury from nitric oxide and superoxide / Proc. Natl. Acad. Sci. U
Bradly, P. P. / 1982 / Measurement of cutaneous inflammation: Estimation of neutrophil content with an enzyme marker / J. Invest. Dermatol 78 : 206 ~ 209
Antolovich, M. / 2002 / Methods for testing antioxidant activity / Analyst 127 : 183 ~ 198
Baik, Jong Seok / 2008 / Chemical Composition and Biological Activities of Essential Oils Extractedfrom Korean Endemic Citrus Species / Journal of Microbiology and Biotechnol
Beckman, J. S. / 1990 / Apparent hydroxyl radical production by peroxynitrite: Implications for endothelial injury from nitric oxide and superoxide / Proc. Natl. Acad. Sci. U
Bradly, P. P. / 1982 / Measurement of cutaneous inflammation: Estimation of neutrophil content with an enzyme marker / J. Invest. Dermatol 78 : 206 ~ 209
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