지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2005.1
- 수록면
- 365 - 370 (6page)
이용수
초록· 키워드
오류제보하기
DNA chip has been used as the genetic reprogramming of cells and its link to cellular phenotype such as angiogenesis. To evalu-ate the angiogenesis related genetic reprogramming more efficiently, we here developed an angioge-nesis-focused cDNA chip containing 153 angioge-nesis related genes arrayed in duplicate on a slide glass. In order to validate the functionality of the angiogenesis-focused cDNA chip, we examined gene expression profiles in HT1080 cells treated with either fetal bovine serum, a well known pro-angio-genic factor, or trichostatin A, a known angiogenesis inhibitor, using the cDNA chip. All duplicate data from the analysis are well matched with each other and gene expression profiles are well consistent with previously reported data. These results demonstrate here can be a useful tool towards angiogenesis- related researches.
목차
등록된 정보가 없습니다.
참고문헌 (22)
참고문헌 신청
/ / Brown PO. Quantitativemonitoring of gene expression patterns with a complementaryDNA microarray. Science 1995 270 : 467 ~ 70
/ / Castronovo V. Histone deacetylases inhibitors as antiangiogenicagents altering vascular endothelial growth factorsignaling. Oncogene 2002 : 427 ~ 36
/ / Cinatl J. Induction of differentiation and suppression of malignantphenotype of human neuroblastoma BE enhancement by combination with interferonalpha.Int J Oncol 2002 :
/ / Friend SH. Drugtarget validation and identification of secondary drug targeteffects using DNA microarrays. Nat Med 1998 4 : 1293 ~ 301
/ / Imamura M. Vascular endothelialgrowth factor-induced tumor angiogenesis and tumorigenicityin relation to metastasis in a HT1080 humanfibrosarcoma cell model. Int J Cance
/ / Castronovo V. Histone deacetylases inhibitors as antiangiogenicagents altering vascular endothelial growth factorsignaling. Oncogene 2002 : 427 ~ 36
/ / Cinatl J. Induction of differentiation and suppression of malignantphenotype of human neuroblastoma BE enhancement by combination with interferonalpha.Int J Oncol 2002 :
/ / Friend SH. Drugtarget validation and identification of secondary drug targeteffects using DNA microarrays. Nat Med 1998 4 : 1293 ~ 301
/ / Imamura M. Vascular endothelialgrowth factor-induced tumor angiogenesis and tumorigenicityin relation to metastasis in a HT1080 humanfibrosarcoma cell model. Int J Cance
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