지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2004.1
- 수록면
- 36 - 42 (7page)
이용수
초록· 키워드
오류제보하기
Recent epidemiological studies sugest that alco-hol consumption is one of the risk factors leading to type 2 diabetes, but the direct efect of ethanol on b-cel gene expresion is not known. Here, using cDNA RDA method, we isolated 43 ethanol- induced genes in pancreatic b-cells, and con-firmed their diferential expresion by Northern were further categorized by the functional criteria based on the published data; Translation, Trans-cription, Metabolism, Signal transduction, Trans-port, Structure, Cytoskeleton, Regulation, or Puta-tive/Unknown genes. The effects of each gene on b-cel function ned to be further investigated, however, the present data strongly sugest that these genes might be related to the metabolic al-terations caused by ethanol as indicated in earlier study. In particular, RPS3 gene expression was implying that ethanol might decrease the metabo-lic activity by oxidative stress in b-cells. Therefore, cloning of these genes in ful-length and the detailed studies of each gene on b-cel functions might provide clues on the pathophysiology of type 2 diabetes caused by alcohol.
목차
등록된 정보가 없습니다.
참고문헌 (20)
참고문헌 신청
/ / Identifying differences in mRNAexpression by representational difference analysis of cDNA : 5640 ~ 8
/ 1861-7 / In vivo modulation of 73 kDa heat shock cognate and78 kDa glucose-regulating protein gene expression in rat liverand brain by ethanol
/ 19891989-97 / Ethanol decreasesbasal insulin secretion from HIT-T15 cells
/ 1997 / Cellular and molecular neuroscienceof alcoholism. : 1 ~ 20
/ 2000 / Protection of insulin-producing RINm5F cells againstcytokine-mediated toxicity through overexpression of antioxidantenzymes : 1123 ~ 30
/ 1861-7 / In vivo modulation of 73 kDa heat shock cognate and78 kDa glucose-regulating protein gene expression in rat liverand brain by ethanol
/ 19891989-97 / Ethanol decreasesbasal insulin secretion from HIT-T15 cells
/ 1997 / Cellular and molecular neuroscienceof alcoholism. : 1 ~ 20
/ 2000 / Protection of insulin-producing RINm5F cells againstcytokine-mediated toxicity through overexpression of antioxidantenzymes : 1123 ~ 30
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
프마이크로어레이 데이터의 유전자 집합 및 대사 경로 분석
유전체소식
2006 .01
-
Molecular Cloning and Characterization of Two Major Endoglucanases from Penicillium decumbens
Journal of Microbiology and Biotechnology
2010 .01
-
Immunofluorescence Localization of Schizosaccharomyces pombe cdc103+ Gene Product
The Journal of Microbiology
1996 .09
-
RFLP Analysis of cry1 and cry2 Genes of Bacillus thuringiensis Isolates from India
Journal of Microbiology and Biotechnology
2012 .01
-
Efficient gene delivery in differentiated human embryonicstem cells
Experimental and Molecular Medicine
2005 .01
-
Statistical Analysis of Gene Expression Data
한국생물정보시스템생물학회 워크샵
2001 .01
-
Informative Gene Selection Method in Tumor Classification
Genomics & informatics
2004 .01
-
Roles of Carbohydrate-Binding Module (CBM) of an Endo-β-1,4- Glucanase (Cel5L) from Bacillus sp. KD1014 in Thermostability and Small-Substrate Hydrolyzing Activity
Journal of Microbiology and Biotechnology
2018 .01
-
Targeting efficiency of α-1,3-galactosyl transferase gene in pig fetal fibroblast cells
Experimental and Molecular Medicine
2003 .01
-
Global Analysis of Gene Expression upon Acid Treatment in Arabidopsis thaliana
The Plant Pathology Journal
2009 .06
-
식물 유전자의 구조와 특성
한국식물학회 심포지움
1987 .01
-
New Aspects of Gene-for-Gene Interactions for Disease Resistance in Plant
The Plant Pathology Journal
2001 .04
-
Identification and Characterization of Human Genes Targeted by Natural Selection
Genomics & informatics
2008 .01
-
State-Space Approach to Modeling Dynamics of Gene Regulation in Networks
한국생물정보시스템생물학회 학술대회
2005 .01
-
Study of the difference of high and low metastasis cell line's gene expression map and metastasis-related genes of adenoid cystic carcinoma
Experimental and Molecular Medicine
2003 .01
-
Finding associations between genes by time-series microarray sequential patterns analysis
한국생물정보시스템생물학회 학술대회
2005 .01
-
The Application of Dual Suicide Gene in Targeted Gene Therapy
한국동물학회 학술대회
1997 .01
-
Finding Interesting Genes Using Reliability in Various Gene Expression Models
Genomics & informatics
2011 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0