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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2009.1
- 수록면
- 61 - 66 (6page)
이용수
초록· 키워드
오류제보하기
A new approach to enhancing the effectiveness of vaccines
is to deliver antigens selectively to dendritic cells
(DC) in situ, via monoclonal antibodies specific for particular
DC surface molecules. This can markedly enhance
CTL responses and, via helper T cells, also enhance
antibody responses. DC activation agents or adjuvants
must also be administered for effective CTL responses,
but in some cases good antibody responses
can be obtained without adjuvants. Here we review the
role of different DC subsets and different DC target molecules
in obtaining enhanced immune responses.
목차
등록된 정보가 없습니다.
참고문헌 (23)
참고문헌 신청
Bonifaz L / 2002 / Efficient targeting of protein antigen to the dendritic cell receptor DEC-205 in the steady state leads to antigen presentation on major histocompatibility
Bonifaz LC / 2004 / In vivo targeting of antigens to maturing dendritic cells via the DEC-205 receptor improves T cell vaccination / J Exp Med 199 : 815 ~ 24
Boscardin SB / 2006 / Antigen targeting to dendritic cells elicits long-lived T cell help for antibody responses / J Exp Med 203 : 599 ~ 606
Bruder D / 2005 / On the edge of autoimmunity: T-cell stimulation by steady-state dendritic cells prevents autoimmune diabetes / Diabetes 54 : 3395 ~ 401
Burgdorf S / 2007 / Distinct pathways of antigen uptake and intracellular routing in CD4 and CD8 T cell activation / Science 316 : 612 ~ 6
Bonifaz LC / 2004 / In vivo targeting of antigens to maturing dendritic cells via the DEC-205 receptor improves T cell vaccination / J Exp Med 199 : 815 ~ 24
Boscardin SB / 2006 / Antigen targeting to dendritic cells elicits long-lived T cell help for antibody responses / J Exp Med 203 : 599 ~ 606
Bruder D / 2005 / On the edge of autoimmunity: T-cell stimulation by steady-state dendritic cells prevents autoimmune diabetes / Diabetes 54 : 3395 ~ 401
Burgdorf S / 2007 / Distinct pathways of antigen uptake and intracellular routing in CD4 and CD8 T cell activation / Science 316 : 612 ~ 6
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