지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
Bisphosphonate (BP) is a useful anti-resorptive agent which decreases the risk of osteoporotic fracture by about 50%. However, recent evidences have shown its strong correlation with the occurrence of atypical femoral fracture (AFF). The longer the patient takes BP, the higher the risk of AFF. Also, the higher the drug adherence, the higher the risk of AFF. It is necessary to ask the patients who are taking BP for more than 3 years about the prodromal symptoms such as dull thigh pain. Simple radiography, bone scan, and magnetic resonance imaging (MRI) are good tools for the diagnosis of AFF. The pre-fracture lesion depicted on the hip dual energy X-ray absorptiometry (DXA) images should not be missed. BP should be stopped immediately after AFF is diagnosed and calcium and vitamin D (1,000 to 2,000 IU) should be administered. The patient should be advised not to put full weight on the injured limb. Daily subcutaneous injection of recombinant human parathyroid hormone (PTH; 1-34) is recommended if the patient can afford it. Prophylactic femoral nailing is indicated when the dreaded black line is visible in the lateral femoral cortex, especially in the subtrochanteric area.
목차
등록된 정보가 없습니다.
참고문헌 (12)
참고문헌 신청
Dell RM / 2012 / Incidence of atypical nontraumatic diaphyseal fractures of the femur / J Bone Miner Res 27 : 2544 ~ 2550
Donnelly E / 2012 / Reduced cortical bone compositional heterogeneity with bisphosphonate treatment in postmenopausal women with intertrochanteric and subtrochanteric fractur
Goh SK / 2007 / Subtrochanteric insufficiency fractures in patients on alendronate therapy: a caution / J Bone Joint Surg Br 89 : 349 ~ 353
Gun-Il Im / 2015 / Pathogenesis, Management and Prevention of Atypical Femoral Fractures / 대한골대사학회지 22 (1) : 1 ~ 8
Kim S / 2014 / Detection of prefracture hip lesions in atypical subtrochanteric fracture with dual-energy x-ray absorptiometry images / Radiology 270 : 487 ~ 495
Donnelly E / 2012 / Reduced cortical bone compositional heterogeneity with bisphosphonate treatment in postmenopausal women with intertrochanteric and subtrochanteric fractur
Goh SK / 2007 / Subtrochanteric insufficiency fractures in patients on alendronate therapy: a caution / J Bone Joint Surg Br 89 : 349 ~ 353
Gun-Il Im / 2015 / Pathogenesis, Management and Prevention of Atypical Femoral Fractures / 대한골대사학회지 22 (1) : 1 ~ 8
Kim S / 2014 / Detection of prefracture hip lesions in atypical subtrochanteric fracture with dual-energy x-ray absorptiometry images / Radiology 270 : 487 ~ 495
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