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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 72 - 78 (7page)
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Purpose: This retrospective study was undertaken to investigate whether increasing amikacin dosage for ciprofloxacin prophylaxis in patients with fluoroquinolone (FQ)-resistant rectal flora reduce infectious complications after transrectal ultrasound-guided prostate biopsy (TRUSPB).Materials and Methods: A total of 430 patients with FQ-resistant rectal flora based on rectal swab cultures were divided into two groups. Patients in both groups were administered ciprofloxacin (400 mg, intravenous [IV], twice daily) on the same day as TRUSPB and one day after biopsy. However, whereas group 1 patients (n=202) were administered a single injection of amikacin (1 g, IV) one hour before TRUSPB, patients in group 2 (n=228) were administered two injections of amikacin (1 g, IV) before one hour TRUSPB and again on the day after TRUSPB.Results: Of the 430 study subjects, 129 (30.0%) showed extended-spectrum beta-lactamase (ESBL) positivity. The overall incidence rate of infectious complications was 2.8% (12/430). Infectious complication rates were 4.0% (8/202) in group 1 and 1.3% (3/228) in group 2 (p=0.075). Urinary tract infection and acute prostatitis were more frequent in group 1 (3.5% vs. 0.4%, p=0.029). Infectious complication rates in ESBL negative patients were 3.4% (5/145) in group 1 and 1.3% (2/156) in group 2, whereas those in ESBL positive patients were 7.0% (4/57) in group 1 and 1.4% (1/72) in group 2.Conclusions: Increasing the dosage of amikacin for ciprofloxacin prophylaxis reduce infectious complications in patients with FQ-resistant rectal flora and to be more effective in ESBL positive patients with FQ-resistant rectal flora.
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참고문헌 (28)
참고문헌 신청
Loeb S / 2011 / Complications after prostate biopsy: data from SEER-Medicare / J Urol 186:1830~1834
Tufan ZK / 2011 / A life-threatening Escherichia coli meningitis after prostate biopsy / Urol J 8:69~71
Wolf JS Jr / 2008 / Best practice policy statement on urologic surgery antimicrobial prophylaxis / J Urol 179:1379~1390
Cek M / 2013 / Antibiotic prophylaxis in urology departments, 2005-2010 / Eur Urol 63:386~394
Feliciano J / 2008 / The incidence of fluoroquinolone resistant infections after prostate biopsy--are fluoroquinolones still effective prophylaxis / J Urol 179:952~955
Tufan ZK / 2011 / A life-threatening Escherichia coli meningitis after prostate biopsy / Urol J 8:69~71
Wolf JS Jr / 2008 / Best practice policy statement on urologic surgery antimicrobial prophylaxis / J Urol 179:1379~1390
Cek M / 2013 / Antibiotic prophylaxis in urology departments, 2005-2010 / Eur Urol 63:386~394
Feliciano J / 2008 / The incidence of fluoroquinolone resistant infections after prostate biopsy--are fluoroquinolones still effective prophylaxis / J Urol 179:952~955
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