갑상선 유두상 암의 경부 림프절 전이에서 발생한 갑상선 역형성 암

조민규; 정재환; 최성원; 김영민; 차원재

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자료유형: 학술저널

저자정보: 조민규 정재환 최성원 김영민 차원재

저널정보: 대한이비인후과학회 부산,울산,경남 지부회 임상이비인후과 임상이비인후과 제29권 제1호

발행연도: 2018.1

수록면: 128 - 132 (5page)

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Anaplastic thyroid carcinoma (ATC) has the most aggressive progression among thyroid malignancies and its prognosis is almost invariably fatal. ATC may arise de novo, but in most cases it develops from a pre-existing well-differentiated thyroid cancer. We present the case of a 77-year-old woman complained of neck mass and pain. She had a history of papillary thyroid carcinoma (PTC) and underwent total thyroidectomy in 14 years ago. 6 years ago, follow-up ultrasonography revealed cervical lymph node enlargement in left level III and fine needle aspiration cytology showed PTC. Because of the reluctance for surgery, the metastatic node was closely observed without re-operation. Ultrasonography guided core needle biopsy for cervical mass was performed and histopathology was consistent with ATC. Rapid deterioration of the patient’s general condition finalized with death within in six months from the initial presentation. Despite its rare occurrence, the possibility of anaplastic transformation from latent cervical metastasis of PTC and aggressive management should be considered.

#Anaplastic thyroid carcinomaㆍCervical metastasisㆍAnaplastic transformation.

참고문헌 (12)

참고문헌 신청

Patel KN / 2006 / Poorly differentiated and anaplastic thyroid cancer / Cancer Control 13(2):119~128

Wein RO / 2011 / Anaplastic thyroid carcinoma: palliation or treatment? / Curr Opin Otolaryngol Head Neck Surg 19(2):113~118

Wiseman SM / 2003 / Anaplastic transformation of thyroid cancer: review of clinical, pathologic, and molecular evidence provides new insights into disease biology and future therapy / Head Neck 25(8):662~670

O'Neill JP / 2013 / Anaplastic thyroid cancer / Oral Oncol 49(7):702~706

Ito Y / 2008 / Prognosis of patients with papillary carcinoma showing anaplastic transformation in regional lymph nodes that were curatively resected / Endocr J 55(6):985~989

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