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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한치매학회 Dementia and Neurocognitive Disorders(대한치매학회지) Dementia and Neurocognitive Disorders(대한치매학회지) 제16권 제2호
- 발행연도
- 2017.1
- 수록면
- 40 - 47 (8page)
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초록· 키워드
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Subjective cognitive decline (SCD) represents subjective complaints about cognitive decline in the absence of objective impairment in neuropsychological tests. Recently, growing evidence has suggested that SCD might be the first symptomatic stage of Alzheimer’s disease (AD) spectrum disorders. However, SCD is a heterogeneous condition mixed with AD and non-AD related conditions. Hence, refinement of evidence from previous reports and standardization of the concept about SCD are needed to define appropriate target population with AD pathology. In this article, we review previous studies involving subjects with SCD, the new proposed research criteria, and characteristics of SCD in the aspect of preclinical AD. Biomarker status of SCD is also addressed. Future researches on SCD require a longitudinal follow-up with sufficient biomarker studies and proper outcome measures.
목차
등록된 정보가 없습니다.
참고문헌 (22)
참고문헌 신청
Dubois B / 2010 / Revising the definition of Alzheimer’s disease:a new lexicon / Lancet Neurol 9 : 1118 ~ 1127
Dufouil C / 2005 / Subjective cognitive complaints and cognitive decline: consequence or predictor? The epidemiology of vascular aging study / J Am Geriatr Soc 53 : 616 ~ 62
Glodzik-Sobanska L / 2007 / Subjective memory complaints: presence, severity and future outcome in normal older subjects / Dement Geriatr Cogn Disord 24 : 177 ~ 184
Hong YJ / 2016 / White matter changes may precede gray matter loss in elderly with subjective memory impairment / Dement Geriatr Cogn Disord 42 : 227 ~ 235
Jack CR Jr / 2013 / Tracking pathophysiological processes in Alzheimer’s disease: an updated hypothetical model of dynamic biomarkers / Lancet Neurol 12 : 207 ~ 216
Dufouil C / 2005 / Subjective cognitive complaints and cognitive decline: consequence or predictor? The epidemiology of vascular aging study / J Am Geriatr Soc 53 : 616 ~ 62
Glodzik-Sobanska L / 2007 / Subjective memory complaints: presence, severity and future outcome in normal older subjects / Dement Geriatr Cogn Disord 24 : 177 ~ 184
Hong YJ / 2016 / White matter changes may precede gray matter loss in elderly with subjective memory impairment / Dement Geriatr Cogn Disord 42 : 227 ~ 235
Jack CR Jr / 2013 / Tracking pathophysiological processes in Alzheimer’s disease: an updated hypothetical model of dynamic biomarkers / Lancet Neurol 12 : 207 ~ 216
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