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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2009.1
- 수록면
- 31 - 40 (10page)
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초록· 키워드
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Objective: This study was carried out to investigate protective effects of Pharmacopuncture Solutions (PSs) made by Carthmi Flos (CF), Cnidii Rhizoma (CR) and Astragali Radix (AR) on C6 glioma cells
Methods: We investigated the effects of PSs on proliferation rates and types of C6 cells, and also investigated the effects on LDH release. In addition, protective effects of PSs on oxidative stress induced by hydrogen peroxide and SOD-like activities were also investigated.
Results: PSs made by CF, CR and AR did not show cytotoxicity in various concentrations. CF-PS and AR-PS elevated levels of proliferation rates significantly. Treatment with CF-PS lowered level of LDH release in C6 cells. In addition, CF-PS and CR-PS showed protective effects on cell death induced by hydrogen peroxide respectively. Finally, CF-PS group showed high level of SOD－like activity compared to that in CR-PS group.
Conclusion: These results suggest that CF-PS can accelerate proliferation of neuroglial cells, and has protective action against oxidative stress, which was involved in anti-oxidative effects such as SOD-like activities. In addition, CR has protective effects against oxidative stress, and AR can accelerate proliferation of neuroglial cells.
목차
등록된 정보가 없습니다.
참고문헌 (31)
참고문헌 신청
Bi J / 2008 / Protective effects of catalpol against H2O2-induced oxidative stress in astrocytes primary cultures / Neurosci Lett. 442 (3) : 224 ~ 227
Corpas FJ / 2001 / Peroxisomes as a source of reactive oxygen species and nitric oxide signal molecules in plant cells / Trends Plant Sci. 6 (4) : 145 ~ 150
Corpas FJ / 2006 / The expression of different superoxide dismutase forms is cell-type dependent in olive (Olea europaea L.) leaves / Plant Cell Physio 47 (7) : 984 ~ 994
Goodman Y / 1994 / Secreted forms of b-amyloid precursor protein protect hippocamal neurons against amyloid b-peptide-induced oxidative injury / Exp. Neurol. 128 : 1 ~ 12
J. Drabowicz / 1994 / in The Syntheses of Sulphones, Sulphoxides and Cyclic Sulphides / John Wiley & Sons : 112 ~ 116
Corpas FJ / 2001 / Peroxisomes as a source of reactive oxygen species and nitric oxide signal molecules in plant cells / Trends Plant Sci. 6 (4) : 145 ~ 150
Corpas FJ / 2006 / The expression of different superoxide dismutase forms is cell-type dependent in olive (Olea europaea L.) leaves / Plant Cell Physio 47 (7) : 984 ~ 994
Goodman Y / 1994 / Secreted forms of b-amyloid precursor protein protect hippocamal neurons against amyloid b-peptide-induced oxidative injury / Exp. Neurol. 128 : 1 ~ 12
J. Drabowicz / 1994 / in The Syntheses of Sulphones, Sulphoxides and Cyclic Sulphides / John Wiley & Sons : 112 ~ 116
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