지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한치매학회 Dementia and Neurocognitive Disorders(대한치매학회지) Dementia and Neurocognitive Disorders(대한치매학회지) 제14권 제1호
- 발행연도
- 2015.1
- 수록면
- 12 - 16 (5page)
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초록· 키워드
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Background and PurposeIn memory clinics, the lumbar puncture (LP) is increasingly being used to evaluate cerebrospinal fluid for biomarkers of Alzheimer’s disease (AD). Post-lumbar puncture headache (PLPH) is the most frequent complication of LP, and can prove to be a barrier for the performance of LP.
MethodsWe retrospectively collected data from 59 subjects (patients with AD and cognitively healthy controls) who were enrolled in a study aimed to identify AD biomarkers via LP. In order to determine whether subjects experienced PLPH, we assessed recorded follow-up telephone interviews. To analyze the association between the occurrence of PLPH and several demographic- and procedure-related factors, a multiple logistic regression analysis with backward stepwise method was performed.
ResultsThe overall frequency of PLPH was 49.15%. PLPH was more frequent in younger subjects and clinical diagnosis was associated with PLPH. The use of cutting-edge needles was also suggested as a statistically significant factor in the development of PLPH, and was determined to be the only factor that could be modified in order to lower the frequency of PLPH.
ConclusionsAge, clinical diagnosis, and needle type were all determined to be predictive factors of PLPH.
목차
등록된 정보가 없습니다.
참고문헌 (20)
참고문헌 신청
Ahmed SV / 2006 / Post lumbar puncture headache: diagnosis and management / Postgrad Med J 82 : 713 ~ 716
Alcolea D / 2014 / Feasibility of lumbar puncture in the study of cerebrospinal fluid biomarkers for Alzheimer’s disease: a multicenter study in Spain / J Alzheimers Dis 39
Blennow K / 1993 / Low frequency of post-lumbar puncture headache in demented patients / Acta Neurol Scand 88 : 221 ~ 223
Christensen H / 2001 / What cognitive changes can be expected with normal ageing? / Aust N Z J Psychiatry 35 : 768 ~ 775
Dubois B / 2007 / Research criteria for the diagnosis of Alzheimer’s disease: revising the NINCDS-ADRDA criteria / Lancet Neurol 6 : 734 ~ 746
Alcolea D / 2014 / Feasibility of lumbar puncture in the study of cerebrospinal fluid biomarkers for Alzheimer’s disease: a multicenter study in Spain / J Alzheimers Dis 39
Blennow K / 1993 / Low frequency of post-lumbar puncture headache in demented patients / Acta Neurol Scand 88 : 221 ~ 223
Christensen H / 2001 / What cognitive changes can be expected with normal ageing? / Aust N Z J Psychiatry 35 : 768 ~ 775
Dubois B / 2007 / Research criteria for the diagnosis of Alzheimer’s disease: revising the NINCDS-ADRDA criteria / Lancet Neurol 6 : 734 ~ 746
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