지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 29 - 42 (14page)
이용수
이 논문의 연구 히스토리 (2)
- 이 논문의 후속연구가 궁금하신가요?
- 연관 학술논문 또는 학술발표를 통해 보다 발전된 연구결과를 확인하실 수 있습니다.
- 이 논문의 연구 히스토리 확인하기
초록· 키워드
오류제보하기
Objectives : Atopic dermatitis accompanies with severe pruritus and collapse of skin barrier, inflammation.
Maifanite could be used as an ointment for skin disease. However, there have been few studies about maifanite uses for atopic dermatitis. We report the anti-inflammatory and promoting skin recovery effects of ionized maifanite on damaged skin barrier with experimentally elicited atopic dermatitis.
Methods : Nc/Nga mice were divided into 3 groups: control group(CON), atopic dermatitis elicited group(AE group), ionized maifanite treated group after atopic dermatitis elicitation(MT group).
After 5% SDS was applied D. pteronyssinus crude extract also applied for 3 weeks to elicit atopic dermatitis-like skin disease. MT group was treated for 3 weeks with ionized maifanite. Ionized maifanite was applied once a day and voluntarily administrated. AE group and control group were treated with normal saline in the same way.
Results : In MT group, skin lesions like eczema were more improved than AE group. p-ERK1/2 positive reaction was reduced in MT group. MMP-9 and substance P positive reaction at dermal papillae was also reduced in MT group. With skin angiogram, capillary vessel decreased in MT group. Also, IL-4 positive reaction cell and STAT-6 positive reaction cell reduced more in MT group than in AE group. NF-κB p65 positive reaction cell and iNOS positive reaction cell also declined more in MT group than in AE group.
Conclusions : It is supposed that ionized maifanite has anti-inflammatory effects on NC/Nga mice’s atopic dermatitis with suppressing IL-4 production and Th2 cell differentiation, and controlling NF-κB activation.
목차
등록된 정보가 없습니다.
참고문헌 (26)
참고문헌 신청
Administration KFD / 2009 / Clinical trial guidelines of herbal medicinal products about atopic dermatitis
Al-Mogairen SM / 2011 / Role of sodium silicate in induction of scleroderma-related autoantibodies in brown Norway rats through oral and subcutaneous administration / Rheuma
Boguniewicz M / 2011 / Atopic dermatitis : a disease of altered skin barrier and immune dysregulation / Immunological Reviews 242 (1) : 233 ~ 246
Cha JY / 2000 / Effect of quartz porphyry supplemented diet on mineral content in tissues of common finch / Journal of Life Science 10 (6) : 543 ~ 547
Cha JY / 2001 / Effect of quartz porphyry on the functional and morphological changes of liver and kidney in common finch and white java sparrow / Journal of Life Science 11
Al-Mogairen SM / 2011 / Role of sodium silicate in induction of scleroderma-related autoantibodies in brown Norway rats through oral and subcutaneous administration / Rheuma
Boguniewicz M / 2011 / Atopic dermatitis : a disease of altered skin barrier and immune dysregulation / Immunological Reviews 242 (1) : 233 ~ 246
Cha JY / 2000 / Effect of quartz porphyry supplemented diet on mineral content in tissues of common finch / Journal of Life Science 10 (6) : 543 ~ 547
Cha JY / 2001 / Effect of quartz porphyry on the functional and morphological changes of liver and kidney in common finch and white java sparrow / Journal of Life Science 11
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
황련 추출물의 아토피피부염 유발 생쥐에서 피부손상 완화 효과
동의생리병리학회지
2019 .01
-
황련 추출물의 아토피피부염 유발 생쥐에서 피부손상 완화 효과
동의생리병리학회지
2019 .04
-
Therapeutic effects of LED fusion of two wavelength bands on Atopic dermatitis of NC/Nga mice
한국실험동물학회 학술발표대회 논문집
2022 .07
-
소아 아토피피부염의 약물치료
대한의사협회지
2022 .10
-
Influence of Weight Loss on Severity of Atopic Dermatitis in a 20-Year-Old Female with Atopic Dermatitis
Annals of Dermatology
2018 .01
-
Influences of Environmental Chemicals on Atopic Dermatitis
Toxicological Research
2015 .06
-
아토피피부염 동물 병태 모델에서 아토탕의 개선효과
대한본초학회지(본초분과학회지)
2016 .01
-
성인 아토피피부염의 사회경제적 관계에 관한 연구
Allergy Asthma & Respiratory Diseases
2015 .01
-
Therapeutic Effects of a Light Emitting Diode at a Variety of Wavelengths on Atopic Dermatitis-Like Skin Lesions in NC/Nga Mice
Annals of Dermatology
2017 .01
-
소아 아토피피부염의 최신 치료
Allergy Asthma & Respiratory Diseases
2021 .01
-
Associations of Atopic Dermatitis With Obesity and Unmarried Status in Young Adults: Evidence for Atopic Dermatitis as a Life-Style Disorder With High Social Impact
Allergy, Asthma & Immunology Research
2016 .01
-
Economic Impact of Atopic Dermatitis in Korean Patients
Annals of Dermatology
2015 .01
-
호마자 추출물이 NC/Nga 생쥐의 아토피 피부염에 미치는 영향
대한한방소아과학회지
2015 .01
-
편백유(Chamaecyparis Obtusa Oil)가 DNCB로 유도된 NC/Nga생쥐의 아토피에 미치는 효과 연구
한방안이비인후피부과학회지
2016 .01
-
아토피피부염 개인건강기록 어플리케이션 개발을 위한 전문가집단 설문조사 연구
한방안이비인후피부과학회지
2016 .01
-
자녀의 아토피 피부염 유병이 주양육자의 정신건강에 미치는 영향
대한보건연구
2017 .01
-
Improvement effect of blackberry extract in atopic dermatitis mouse model
한국실험동물학회 학술발표대회 논문집
2021 .07
-
Hataedock Treatments for Dermatophagoides Farinae-induced Atopic Dermatitis in NC/Nga Mice Treated with High-fat Diet
동의생리병리학회지
2018 .01
-
Anti-atopic effect of Persicaria longiseta (Bruijn) Kitag in atopic dermatitis murine model induced by 2,4-dinitrochlorobenzene
한국실험동물학회 학술발표대회 논문집
2022 .07
이 논문의 저자 정보
최근 본 자료
댓글(0)
0