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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2006.1
- 수록면
- 103 - 114 (12page)
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초록· 키워드
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Objective : The purpose of this study was to investigate effects of Taklihwajung-Tang on the proliferation of
cancer cells and immunocytes focusing arround combined effects of anticarcinogen.
Materials and Method : We used Taklihwajung-Tang extract(THT) with freeze-dried, 8wks-old male balb/c mice
and cancer cell lines(L1210, S-180) for this study. The proliferation of cells was tested using a colorimetric
tetrazoliun assay(MTT assay).
Results and Conclusion : The results of this study were obtained as follow ;
1. THT was significantly showed cytotoxicity on the L1210 cell lines and S-180 cell lines.
2. THT was significantly increased in the proliferation of thymocytes and splenocytes in vitro.
3. In combined effects of THT and vincristine(0.005㎎/㎏), THT was significantly inhibited proliferation of S-180
cell lines compared with positive control group.
4. In combined effects of THT and vincristine(0.005㎎/㎏), THT was significantly decreased in the weight of
sarcoma compared with positive control group.
5. In combined effects of THT and vincristine, THT was significantly inhibited the hematological side reaction
compared with positive control group.
The present author thought that THT had action of anti-cancer and immuno-activity, and in combined effects of
vincristine, THT had recoverable effects on damage by anticarcinogen.
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