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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2006.1
- 수록면
- 93 - 102 (10page)
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초록· 키워드
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Objective : Gamisibgi-San was a drug that treated carbuncle and cellulitis. So, the purpose of this Study was to
investigate effects of Gamisibgi-San on the anti-cancer and proliferation of immunocytes.
Materials and Method : We used Gamisibgi-San extract(GMSGS) with freeze-dried, 8wks-old male mice and
cancer cell lines(L1210, S-180) for this Study. The cytotoxicity and proliferation of cells were tested using a
colorimetric tetrazoliun assay(MTT assay).
Results and Conclusion : The results of this Study were obtained as follow ;
1. GMSGS was significantly showed cytotoxicity on the L1210 cell lines and S-180 cell lines.
2. GMSGS was significantly increased in the proliferation of thymocytes and splenocytes in vitro.
3. GMSGS was significantly decreased in the proliferation of L1210 cells in L1210 cells transplanted mice.
4. GMSGS was significantly decreased in the Weight of Sarcoma in S-180 cells transplanted mice.
5. GMSGS was significantly increased in the Period of Survive in S-180 cells transplanted mice.
The present author thought that GMSGS had action of anti-cancer by becoming immunocytes activity(proliferation
of thymocytes and splenocytes).
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