지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2010.1
- 수록면
- 158 - 168 (11page)
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초록· 키워드
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Objective : Jeungson-Ojeok-Hwan Bijukbang(JOH) has been used to treat patients with tumor etc. In the theory of Korean medicine, JOH can treat Juk-Chui. JOH is known to have treat Juk-Chui. Juk-Chui is analogous to tumor.
Methods : For these reasons, the present study was designed to investigate the effects of JOH on solid tumor in mice in terms of immune-potentiating and direct cytotoxic action of JOH in vitro and vivo study.
The present author investigated thymocyte and splenocyte proliferation to confirm immune-potentiating activity of JOH and also investigated tumor/body weight ratio and survival rates in tumor bearing mice.
Results : In this study, administration of JOH decreased tumor/body weight ratio significantly, and prolonged survival duration compared to non-treated control. In addition, treatment with JOH suppressed proliferation rate of Sarcoma 180 (S-180) cells significantly, and elevated proliferation rates of thymocytes isolated from normal mice. These results were co-related with in vivo study.
Conclusion : these results suggest that JOH is useful to treat patient with solid tumor, because JOH has direct toxic action for tumor cell and immune-potentiating action for T cells. Further study will need to elucidate exact mechanisms related in anti-cancer action of JOH.
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등록된 정보가 없습니다.
참고문헌 (39)
참고문헌 신청
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Hyung Woo Kim / 2007 / Therapeutic Efficacy of Extracts from Root of Acnthopanax Sessiliflorus as Anti-cancer Drug ; in vivo and in vitro Study / 동의생리병리학회지 21 (2) :
Kriukova IN / 1983 / Expression of Thy 1 thymocyte differentiation antigen in mouse mammary cancer cells in vitro / Biull Eksp Biol Med 96 (8) : 81 ~ 84
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Mizel, S.B / 1979 / Regulation of lymphocyte-activating factor (LAF) production and secretion in P388D1 cells ; identification of high molecular weight precursors of LAF / J
Hyung Woo Kim / 2007 / Therapeutic Efficacy of Extracts from Root of Acnthopanax Sessiliflorus as Anti-cancer Drug ; in vivo and in vitro Study / 동의생리병리학회지 21 (2) :
Kriukova IN / 1983 / Expression of Thy 1 thymocyte differentiation antigen in mouse mammary cancer cells in vitro / Biull Eksp Biol Med 96 (8) : 81 ~ 84
Mari M / 2006 / Evaluation of the estrogenic activities of some pesticides and their combinations using MtT/Se cell proliferation assay / International Journal of Hygiene an
Mizel, S.B / 1979 / Regulation of lymphocyte-activating factor (LAF) production and secretion in P388D1 cells ; identification of high molecular weight precursors of LAF / J
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