지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2014.9
- 수록면
- 147 - 155 (9page)
이용수
초록· 키워드
오류제보하기
It has well studied that immune cells are strongly related to tumor progression and tumor suppression. To identify the difference of immune cell between tumor bearing mice and normal mice, we examined systemically the immune cell of CT26 tumor bearing mice on 21 days after tumor cell administration. As previously reported, CD4+ and CD8+ T cells population of tumor bearing mice significantly decreased 38% and 30% on day 21 compared to that of normal mice, respectively. All subpopulation of CD4 and CD8+ T cell significantly decreased, except CD49b+ T cell subpopulation. But, myeloid cell population (CD11b<SUP>high</SUP> and all Gr-1+ subpopulation) of tumor bearing mice significantly increased on day 21. Especially, all subpopulation of CD11b+Gr-1+ cell of tumor bearing mice significantly increased on day 21. Also, Foxp3+CD25<SUP>high</SUP> CD4 T cell (regulatory T cells) population significantly increased on day 21. These results suggest that tumor can induce the decline of T lymphocyte and the expansion of
myeloid cells and regulatory T cells, and provide the basic information for the study of tumor immunology.
myeloid cells and regulatory T cells, and provide the basic information for the study of tumor immunology.
목차
INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION
REFERENCES
참고문헌 (30)
참고문헌 신청
1. [학술지(정기간행물)] - Alexander JP / 1993 / T-cells infiltrating renal cell carcinoma display a poor proliferative response even though they can produce interleukin 2 and express interleukin 2 receptors / Cancer Research 53 : 1380 ~ 1387
2. [학술지(정기간행물)] - Balkwill F / 2004 / Cancer and the chemokine network / Nature Reviews Cancer 4 : 540 ~ 550
3. [학술지(정기간행물)] - Buell JF / 2005 / Malignancy after transplantation / Transplantation 80 : S254 ~ S264
4. [학술지(정기간행물)] - Coussens LM / 2002 / Inflammation and cancer / Nature 420 : 860 ~ 867
5. [학술지(정기간행물)] - Dunn GP / 2002 / Cancer immunoediting: From immunosurveillance to tumor escape / Nature Immunology 3 : 991 ~ 998
2. [학술지(정기간행물)] - Balkwill F / 2004 / Cancer and the chemokine network / Nature Reviews Cancer 4 : 540 ~ 550
3. [학술지(정기간행물)] - Buell JF / 2005 / Malignancy after transplantation / Transplantation 80 : S254 ~ S264
4. [학술지(정기간행물)] - Coussens LM / 2002 / Inflammation and cancer / Nature 420 : 860 ~ 867
5. [학술지(정기간행물)] - Dunn GP / 2002 / Cancer immunoediting: From immunosurveillance to tumor escape / Nature Immunology 3 : 991 ~ 998
이 논문의 저자 정보
최근 본 자료
댓글(0)
0