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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 1 - 10 (10page)
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Objectives : Oxidation by active oxygen in the body, phototoxicity and photoallergic interest has grown,antioxidant and phototoxicity inhibiting substances for research progress. The purpose of this study was toexamine the effects on antioxidant and phototoxicity of Rubus coreanus Fruits.
Meterial and Methods : Hs68 cell lines using the DPPH radical scavenging activity, cytotoxic, phototoxicinhibitory activity and apoptosis were measured.
Results : 1. In MTT assay, the concentrations of Rubus coreanus Fruits that were used on the test had nocytotoxicity.
2. In DPPH radical scavenging activity, the concentration of 50 ㎍/㎖, 100 ㎍/㎖ anti-oxidant effect ofRubus coreanus Fruits was statistically significant increased than control group in dose-dependantly.
3. In phototoxic inhibitory activity, Rubus coreanus Fruits dose-dependently increased the cell viabilityof Hs68 cell lines.
4. The concentration of 50 ㎍/㎖ Rubus coreanus Fruits inhibited the enrichment of nucleus in theHs68 cell stimulated with UVB.
Conclusions : These results indicate that Rubus coreanus Fruits has anti-oxidant effects and Phototoxic InhibitoryActivity. If further study is performed, the use of Rubus coreanus Fruits will be valuable andbeneficial in the therapy of skin aging and damage.
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참고문헌 (28)
참고문헌 신청
B Halliwell / 1987 / The deoxyribose method : A simple"test-tube"assay for determination of rate constants for reactions of hydroxyl radicals / Analytical Biochemistry 165 :
Choi J / 2003 / Antinociceptive and antiinflammatory effects of Niga-ichigoside F1and 23-hydroxytormentic acid obtained from Rubus coreanus / Biol Pharm Bull 26 (10) : 1436
Cimino F / 2007 / Protective effects of a red orange extract on UVB-induced damage in human keratinocytes / Biofactors 30 (2) : 129 ~ 138
EN Frankel / 1996 / Antioxidants in lipid foods and their impact on food quality / Food Chemistry 57 : 51 ~ 55
Ferguson J / 1982 / A study of benoxaprofen-induced photosensitivity / Br. J. Dermatol 107 (4) : 429 ~ 442
Choi J / 2003 / Antinociceptive and antiinflammatory effects of Niga-ichigoside F1and 23-hydroxytormentic acid obtained from Rubus coreanus / Biol Pharm Bull 26 (10) : 1436
Cimino F / 2007 / Protective effects of a red orange extract on UVB-induced damage in human keratinocytes / Biofactors 30 (2) : 129 ~ 138
EN Frankel / 1996 / Antioxidants in lipid foods and their impact on food quality / Food Chemistry 57 : 51 ~ 55
Ferguson J / 1982 / A study of benoxaprofen-induced photosensitivity / Br. J. Dermatol 107 (4) : 429 ~ 442
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