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학술저널
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연세대학교 의과대학 Yonsei Medical Journal Yonsei Medical Journal 제57권 제1호
발행연도
2016.1
수록면
269 - 271 (3page)

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We describe herein a case of an impending corneal perforation with a large descemetocele in a patient with previous penetratingkeratoplasty (PKP) that subsequently was treated with an emergent lamellar keratoplasty using frozen preserved cornea. A76-year-old male patient, who had a PKP, presented with a completely whitish and edematous graft accompanied by large epithelialdefects. Although antibiotics and antiviral agents were tried for three days, the corneal stroma abruptly melted, except forthe Descemet’s membrane and endothelium. Cryopreserved corneal tissue that was kept at -80°C was thawed and sutured on topof the remaining Descemet’s membrane and endothelium. Pathological and microbiological tests were conducted using the remainingdonor and recipient corneal tissues. After tectonic corneal transplantation on top of a large descemetocele, a healthygraft and relatively clear interfaces between graft-host junctions were maintained without serious adverse reactions throughout 6month follow-up period. Microbiological evaluations of donor tissue at the time of thawing and tissue preparation were done,and the results were all negative. Tissue that was taken intraoperatively from the recipient cornea also showed negative microbiologicalresults. In conclusion, tectonic lamellar keratoplasty, using cryopreserved corneal tissue, only onto the remaining Descemet’smembrane and endothelium in an emergent condition, was a safe and effective treatment.

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