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논문 기본 정보

자료유형
학술저널
저자정보
Ye Eun Han (University of Ulsan College of Medicine) Ho Seok Chung (University of Ulsan College of Medicine) 이훈 (울산대학교) 김재용 (울산대학교) 차흥원 (서울아산병원)
저널정보
대한안과학회 Korean Journal of Ophthalmology Korean Journal of Ophthalmology 제36권 제5호
발행연도
2022.4
수록면
131 - 137 (7page)
DOI
10.3341/kjo.2021.0161

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Purpose: To evaluate the clinical outcomes of nanothin Descemet stripping automated endothelial keratoplasty (DSAEK) inKorean patients with corneal endothelial dysfunction.Methods: We retrospectively reviewed medical records of the patients who underwent nanothin DSAEK (graft thickness≤50 μm) due to corneal endothelial dysfunction and followed up more than 1 year. We evaluated best-corrected visual acuity(BCVA), central corneal thickness, and corneal endothelial cell density at preoperative and 1, 3, 6, and 12 months postoperatively.Results: Sixteen eyes of 16 patients with the mean follow-up period of 13.00 ± 0.96 months were included. The mean graftthickness after deswelling was 45.25 ± 4.59 μm (range, 38.0?50.0 μm). The mean logarithm of the minimum angle of resolutionBCVA improved from 1.37 ± 0.53 preoperatively to 0.68 ± 0.46, 0.55 ± 0.35, 0.40 ± 0.25, and 0.39 ± 0.25 at 1, 3, 6, and12 months postoperatively (p = 0.005, p < 0.001, p < 0.001, and p < 0.001), respectively. The mean central corneal thicknessimproved from 752.00 ± 129.11 to 555.75 ± 54.66 μm at 12 months postoperatively (p = 0.006). The mean graft endothelialcell density decreased from 2,859.62 ± 228.34 to 1,542.25 ± 627.34 cells/mm2 at 12 months postoperatively (p = 0.012). Thepostoperative complications included increased intraocular pressure (n = 3, 18.75%) and graft dislocation (n = 1, 6.25%), all ofwhich were successfully managed by anterior chamber paracentesis or rebubbling. No other serious complications were encountered.Conclusions: Nanothin DSAEK produced significant and stable visual improvements without severe postoperative complicationsin Korean patients with corneal endothelial dysfunction.

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