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자료유형
학술저널
저자정보
Tiezhu Lin (Department of Vitreous and Retina He Eye Specialist Hospital) Hong Ye (Department of Vitreous and Retina He Eye Specialist Hospital) Emmanuel Eric Pazo (Department of Vitreous and Retina He Eye Specialist Hospital) Guangzheng Dai (Department of Vitreous and Retina He Eye Specialist Hospital) Yang Xia (Department of Vitreous and Retina He Eye Specialist Hospital) Wei He (Department of Vitreous and Retina He Eye Specialist Hospital)
저널정보
대한안과학회 Korean Journal of Ophthalmology Korean Journal of Ophthalmology 제35권 제4호
발행연도
2021.1
수록면
255 - 260 (6page)

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Purpose: To evaluate the effect of corneal nerves assessment on predicting corneal complications following pars plana vitrectomy(PPV). Methods: In this prospective single-center cohort study, 94 patients (94 eyes) received PPV, and were divided into postoperativegroups with and without corneal complications. All eyes had corneal nerve fiber length (CNFL), corneal nerve fiberdensity, and branch density of corneal nerve fibers assessed and calculated with Image J preoperatively. Multivariate logisticregression analysis was used to identify corneal nerve fiber parameters that correlated to post-operative corneal complications. Receiver operator characteristic curve analysis was performed to identify the optimal cut-off point of the cornealfibers’ parameters for predicting corneal complications after PPV. Results: Eleven eyes (11.70%) developed corneal complications at 1 week after PPV. There was significant difference betweenCNFL (19.44 ± 6.88 vs. 26.84 ± 7.53, p = 0.003), corneal nerve fiber density (28.82 ± 9.91 vs. 37.10 ± 10.16, p = 0.013) andbranch density of corneal nerve fibers (55.84 ± 21.08 vs. 82.04 ± 31.89, p = 0.01) in two groups, respectively. Receiver operatorcharacteristic analysis showed that the optimal cutoff value of CNFL to predict corneal complications following PPV was<26.495 mm/mm2. Conclusions: The decrease of CNFL may predict corneal complications following PPV. Regular preoperative corneal confocalmicroscopy test in PPV patients could be considered.

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