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학술저널
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연세대학교 의과대학 Yonsei Medical Journal Yonsei Medical Journal 제56권 제5호
발행연도
2015.1
수록면
1,421 - 1,427 (7page)

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Purpose: Hypoxemia during one-lung ventilation (OLV) remains a serious problem, particularly in the supine position. We investigatedthe effects of alveolar recruitment (AR) and positive end-expiratory pressure (PEEP) on oxygenation during OLV in the supineposition. Materials and Methods: Ninety-nine patients were randomly allocated to one of the following three groups: a control group (ventilationwith a tidal volume of 8 mL/kg), a PEEP group (the same ventilatory pattern with a PEEP of 8 cm H2O), or an AR group (an AR maneuver immediately before OLV followed by a PEEP of 8 cm H2O). The tidal volume was reduced to 6 mL/kg during OLV in all groups. Blood gas analyses, respiratory variables, and hemodynamic variables were recorded 15 min into TLV (TLVbaseline), 15 and 30 min after OLV (OLV15 and OLV30), and 10 min after re-establishing TLV (TLVend). Results: Ultimately, 92 patients were analyzed. In the AR group, the arterial oxygen tension was higher at TLVend, and the physiologicdead space was lower at OLV15 and TLVend than in the control group. The mean airway pressure and dynamic lung compliancewere higher in the PEEP and AR groups than in the control group at OLV15, OLV30, and TLVend. No significant differences in hemodynamic variables were found among the three groups throughout the study period. Conclusion: Recruitment of both lungs with subsequent PEEP before OLV improved arterial oxygenation and ventilatory efficiencyduring video-assisted thoracic surgery requiring OLV in the supine position.

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