지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2008.1
- 수록면
- 150 - 157 (8page)
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초록· 키워드
오류제보하기
Puropose: The efficacy of finasteride in the treatment of hematuria associated with benign prostatic
hyperplasia (BPH) is well known. Recent studies have also shown that finasteride reduce angiogenesis
and prostatic bleeding associated with BPH. We evaluated that pretreatment with finasteride
could decrease perioperative bleeding associated with transurethral resectrion of prostate
(TURP) in this way.
Material and methods: A total of 56 patients who underwent TURP due to BPH between January
2004 and August 2006 were evaluated. Of the patients, 30 recieved pretreatment with finasteride
5mg daily (group 1) while 26 did not undergo any pretreatment (control group). In the group 1,
17 had pretreatment period of 3months or more (group 2). In all patients we evaluated the degree
of perioperative bleeding, intended as a reduction tendency in hemoglobin (Hb) and hematocrit
(Hct) value in the 24 h following TURP. Also, we evaluated the correlation of the preoperative
factor and postoperative change of Hb and Hct.
Results: Difference of reduction tendency in Hb and Hct between group 1 and control group
was not significant (p=0.86, 0.95, respectively). Difference between group 2 and control was not
significant (p=0.56, 0.29, respectively). The change of Hb and Hct correlated with prostate volume,
significantly (p=0.006, 0.010). Also, operation time was correlated with the change of Hb and Hct
(p=0.006, 0.011).
Conclusions: There were no significant difference of the perioperative bleeding according to
finasteride medication or medication duration. (J Korean Continence Soc 2008;12:150-7)
목차
등록된 정보가 없습니다.
참고문헌 (24)
참고문헌 신청
Carlin BI / 1997 / Role of finasteride in the treatment of recurrent hematuria secondary to benign prostatic hyperplasia / Prostate 31 : 180 ~ 182
Crea G / 2005 / Inferrera A. Pre-surgical finasteride therapy in patients treated endoscopically for benign prostatic hyperplasia / Urol Int 74 : 51 ~ 53
Donohue JF / 2005 / F
Foley SJ / 2000 / A prospective study of the natural history of hematuria associated with benign prostatic hyperplasia and the effect of finasteride / J Urol 163 : 496 ~ 498
Gormley GJ / 1992 / The effect of finasteride in men with benign prostatic hyperplasia. The Finasteride Study Group / N Engl J Med 327 : 1185 ~ 1191
Crea G / 2005 / Inferrera A. Pre-surgical finasteride therapy in patients treated endoscopically for benign prostatic hyperplasia / Urol Int 74 : 51 ~ 53
Donohue JF / 2005 / F
Foley SJ / 2000 / A prospective study of the natural history of hematuria associated with benign prostatic hyperplasia and the effect of finasteride / J Urol 163 : 496 ~ 498
Gormley GJ / 1992 / The effect of finasteride in men with benign prostatic hyperplasia. The Finasteride Study Group / N Engl J Med 327 : 1185 ~ 1191
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