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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2004.1
- 수록면
- 68 - 70 (3page)
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초록· 키워드
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The overall goal of our research projects is to develop effective immunotherapeutic regimens, particularly combining vaccine and gene therapy/ cell therapy strategies. For the development of clinically effective immunotherapy for brain cancers, the following issues are considered to be particularly important: 1) Induction of effective immune responses against tumors (afferent arm of the immune response), 2) Delivery of immune effector cells to the target tumor sites and maintaining the activity of the effector cells (efferent arm), 3) For specificBrief Communication
and safe immunotherapy, specific brain tumor rejection antigens have to be identified, 4) Feasibility, safety and efficacy need to be tested in a series of clinical trials. The following presentation summarizes my research projects and demonstrates how each plan will fit in the whole schema of designing successful immunotherapeutic strategies for brain cancers.
In this presentation, I would like to focus on our clinical and basic studies related to the vaccine strategies for patients with glioma, and modulation of tumor-microenvironment using bone-marrow derived stroma cells as vehicles for cytokine- gene delivery.
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등록된 정보가 없습니다.
참고문헌 (12)
참고문헌 신청
/ 1998 / Bone marrow derived dendritic cells pulsed with a tumor specific peptide elicit effective anti-tumor immunity against intracranial neoplasms 78 : 196 ~ 201
/ 1999 / Effective cytokine gene therapy against an intracranial glioma using a retrovirally transduced IL-4 plus HSV-TK tumor vaccine 6 : 219 ~ 226
/ 1999 / Final maturation of dendritic cells is associated with impaired responsiveness to IFN- gamma and to bacterial IL-12 inducers: decreased ability of mature dendritic c
/ 1999 / Reciprocal control of T helper cell and dendritic cell differentiation 36 : 1183 ~ 1186
/ 1999 / T-cell priming by type-1 and type-2 polarized dendritic cells: the concept of a third signal 20 : 561 ~ 567
/ 1999 / Effective cytokine gene therapy against an intracranial glioma using a retrovirally transduced IL-4 plus HSV-TK tumor vaccine 6 : 219 ~ 226
/ 1999 / Final maturation of dendritic cells is associated with impaired responsiveness to IFN- gamma and to bacterial IL-12 inducers: decreased ability of mature dendritic c
/ 1999 / Reciprocal control of T helper cell and dendritic cell differentiation 36 : 1183 ~ 1186
/ 1999 / T-cell priming by type-1 and type-2 polarized dendritic cells: the concept of a third signal 20 : 561 ~ 567
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