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Purpose: We sought to determine whether early clinical performance of new posterior stabilized (PS) knee system, the Vega­PS (Aesculap), is better than that of two established total knee arthroplasty (TKA) prostheses, the E.motion­PS (Aesculap) and the Genesis II (Smith & Nephew) in terms of functional outcomes, patient satisfaction, and incidence of adverse events.Materials and Methods: We compared the clinical outcomes of 206 consecutive TKAs using Vega­PS with those of 205 TKAs using E.motion­PS and 216 TKAs using Genesis II at 2 years of follow­up.Results: Overall, the knees with the Vega­PS had better functional outcome scores than the knees with the E.motion­PS, but had similar outcome scores to the knees with the Genesis II, as evident from the American Knee Society knee score (94.2 vs. 92.5 vs. 93.2), Western Ontario McMaster Universities Osteoarthritis (WOMAC) stiffness index (1.8 vs. 2.3 vs. 2.0), WOMAC function index (11.8 vs. 16.8 vs. 18.5), Short Form 36 (SF­36) physical component summary score (41.9 vs. 39.3 vs. 41.6), and SF­36 mental component summary score (50.0 vs. 45.8 vs. 46.9). Patient satisfaction was higher in the Vega­PS and Genesis II groups than the E.motion­PS group. No notable group differences were found in terms of the incidence of adverse events.Conclusions: The Vega­PS, a newly developed PS fixed bearing prosthesis, had comparable or superior clinical performance in comparison with the two established fixed or mobile bearing PS prostheses.

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