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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 40 - 47 (8page)
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Granulosa cells, which surround the oocyte within the ovarian follicle, play an essential role in creating conditions required for the development of oocytes and follicles. The solute carrier family (SLC) is comprised of influx transporters of steroidal hormones, various drugs, and several other substrates. The differential expression of selected DEGs was confirmed using in situ hybridization analysis. SLC23A3 and SLC39A10 were highly expressed in the ovary. The SLC39A10 gene was expressed in the primordial follicle stage, but SLC23A3 was expressed in the growing follicle stage. Contrastingly, the expression of SLC23A3 was increased in granulosa cells at the growing follicle stage. The differential expressions of SLC23A3 and SLC39A10 between the primordial and primary follicles were additionally confirmed by using follicle isolations. The gene expression profile from the present study may provide insight for future studies on the mechanism(s) involved in primordial-primary follicular transition and suggestions to promote follicular development in ovarian dysfunction.
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참고문헌 (26)
참고문헌 신청
Ambekar AS / 2013 / Proteomic analysis of human follicular fluid: A new perspective towards understanding folliculogenesis / J Proteomics 87 (7) : 68 ~ 77
Ane K / 2012 / The gap junction channel protein connexin 43 is covalently modified and regulated by SUMOylation / J Biol Chem 287 (19) : 15851 ~ 15861
Blondin P / 1995 / Oocyte and follicular morphology as determining characteristics for developmental competence in bovine oocytes / Mol Reprod Dev 41 (1) : 54 ~ 62
Christenson LK / 2010 / MicroRNA control of ovarian function / Anim Reprod 7 (3) : 129 ~ 133
De Loos FAM / 1994 / Follicular wall maintains meiotic arrest in bovine oocytes cultured in vitro / Mol Reprod Dev 39 (2) : 162 ~ 165
Ane K / 2012 / The gap junction channel protein connexin 43 is covalently modified and regulated by SUMOylation / J Biol Chem 287 (19) : 15851 ~ 15861
Blondin P / 1995 / Oocyte and follicular morphology as determining characteristics for developmental competence in bovine oocytes / Mol Reprod Dev 41 (1) : 54 ~ 62
Christenson LK / 2010 / MicroRNA control of ovarian function / Anim Reprod 7 (3) : 129 ~ 133
De Loos FAM / 1994 / Follicular wall maintains meiotic arrest in bovine oocytes cultured in vitro / Mol Reprod Dev 39 (2) : 162 ~ 165
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