조혈모세포이식 환자의 비부비동염에 대한 임상적 고찰

김성원; 이창훈; 유영화; 김주환; 조진희; 윤희로; 김희제; 김춘추

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자료유형: 학술저널

저자정보: 김성원 이창훈 유영화 김주환 조진희 윤희로 김희제 김춘추

저널정보: 대한이비인후과학회 대한이비인후-두경부외과학회지 대한이비인후과학회지 두경부외과학 제47권 제12호

발행연도: 2004.1

수록면: 1,236 - 1,240 (5page)

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Background and Objectives：As a result of increasing the use of hematopoietic stem cell transplantation (HSCT) for hematologic malignancies and certain solid tumors, more patients have become susceptible to infection. Sinonasal infections in patients with HSCT frequently cause problems which are sometimes fatal. The purpose of this study is to determine the clinical features of sinonasal infections in the immunocompromised patients who received HSCT and to suggest a proper evaluation of these patients. Materals and Method：We reviewed retrospectively 1814 patients who had received HSCT in St. Mary’s hospital from August 1995 to May 2003 to determine the clinical features of sinonasal infections in these patients and to analyze the correlation between sinonasal infection of pre- and post-HSCT. Results：403 patients (22.2%) had sinonasal infections. The infection occurred before HSCT in 206 patients (11.3%), whereas it occurred after HSCT in 197 patients (10.8%). Of 197 patients (27.4%) 54 had previously sinonasal infections. Conclusion：Sinonasal infection in the patients of pre-HSCT increased incidence of post-HSCT sinonasal infection. Early detection using endoscopic examination and sinus computed tomography scan as well as employing an aggressive combined treatment of medical and surgical modalities are essential for the treatment of sinonasal infections in the HSCT patients.

#부비동염·조혈모세포이식. #Sinusitis· Hematopoietic stem cell transplantation.

참고문헌 (18)

참고문헌 신청

/ 1979 / Infections complicationsof human bone marrow transplantation 58 : 1 ~ 31

/ 1985 / Sinusitis immunodeficient and immunosuppressed patients 95 : 29 ~ 33

/ 1991 / Functional endoscopicsinus surgery in the immunocompromised child 105 : 818 ~ 825

/ 1991 / Infections after allogeneic bone marrow transplantation-an analysisof 50 consecutive cases 41 : 103 ~ 111

/ 1991 / Riskfactor in the development of acute sinusitis immunocompromisedpatients 5 : 103 ~ 108

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