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Subject

Immunotherapy in Head and Neck Squamous Cell Cancer
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논문 기본 정보

Type
Academic journal
Author
Journal
대한이비인후과학회 Clinical and Experimental Otorhinolaryngology Clinical and Experimental Otorhinolaryngology 제11권 제4호 KCI Accredited Journals
Published
2018.1
Pages
217 - 223 (7page)

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Immunotherapy in Head and Neck Squamous Cell Cancer
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Abstract· Keywords

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Prognosis in relapsed metastatic head and neck squamous cell cancer (RM-HNSCC) is dismal. Platinum based chemotherapy in combination with Cetuximab is used in first-line setting, while no further validated options are available at progression. Immunotherapy has produced durable clinical benefit in some patients with RM-HNSCC although the premises are several patients are nonresponders. Studies are ongoing to determine predictive factors and the ideal setting/combination of novel immunotherapies. In this paper, we discuss the past and present of immunotherapy in head and neck cancer and provide an up-to-date information regarding the potential ways to improve immunotherapy outcomes in HNSCC.

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