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Background and Objectives:Papilary microcarcinoma of the thyroid gland (PMC) is defined as a papilary thyroid cancer (PTC) measuring les than 1 cm in its diameter. PMC is frequently diagnosed today, mainly as a result of the wide use of neck ultrasonography and fine needle aspiration biopsy. Despite the overal excelent prognosis for patients with PMC, the extent of thyroid resection and the necessity of lymph node disection have become the isues of controversy. The rising incidence of the PMC among PTC necesitates the identification of prognostic factors and standardization of treatment protocols. Therefore, to evaluate the characteristics of PMC, we reviewed our experiences. Subjects and Method:Between 2000 and 2005, 265 patients underwent thyroid surgery and 194 patients showed PTC. Of these patients, 53 patients (27.3%) had PMC (9 male, 44 female, mean age 50.1 years). The data from these patients were retrospectively analyzed. Results:The mean tumor size was 7.19 mm. (77% ) and the combined thyroid diseases were found in 35 patients (66% ). Twelve patients (27.9%) had multifocal microcarcinomas and in 11 patients (20.8%) had extrathyroidal invasion. Lymph node metastasis was found in 18 patients (33.9%). Lymph node metastasis was significantly asociated with the presence of extrathyroidal invasion (p= 0.031), lymph node metastasis (p= 0.008)PMCs over 5 mm in size. Conclusion:These clinical characteristics may be considered as prognostic factors of the PMC. So the treatment modalities should be chosen taking into consideration of the various clinical factors. (Korean J Otorhinolaryngol-Head Neck Surg 2007 ;50 :627-31)

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