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Chronic suppurative otitis media is one of the most common diseases in the otologic field. Along with development and widespread use of antibiotics, the kinds of pathogenic microorganisms and their resistance to antibiotics have been changed. It is thus significant to know the current trend of species and resistance rates of pathogens for choosing appropriate antibiotics. To investigate the current bacteriology of chronic suppurative otitis media and compare the current results with previous results. Subjects and Method:A retrospective study about chronic otitis media patients with otorrhea was performed from Jan, 2000 to Dec, 2005. Results:The most commonly identified pathogenic bacterium was methicillin-resistant Staphylococcus aureus (MRSA). The next frequent pathogenic organisms were Pseudomonas, Coagulase (-) Staphylococcus (CNS) and methicillin-sensitive Staphylococcus aureus (MSSA). Conclusion:There was difference between the results of the present study and previous results regarding pathogenic organisms and antibiotics-sensitivity. Continuous and periodic surveillance about pathogens and antibiotics resistance is necessary to guide appropriate antibacterial therapy. (Korean J Otorhinolaryngol- Head Neck Surg 2008;51:9-15)

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