빅데이터를 이용한 소아 중이염과 천식의 연관성 분석

홍창의; 박준철; 정준희; 장정현; 임현선; 최현승

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자료유형: 학술저널

저자정보: 홍창의 박준철 정준희 장정현 임현선 최현승

저널정보: 대한이비인후과학회 대한이비인후-두경부외과학회지 대한이비인후과학회지 두경부외과학 제60권 제10호

발행연도: 2017.1

수록면: 497 - 503 (7page)

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Background and Objectives Pediatric otitis media is closely related to upper respiratory illness and is one of the most common causes of hospital visiting and antibiotic prescription. Although there are many studies of asthma with other upper respiratory tract infections, few studies have investigated the relationship between asthma and otitis media. This study estimated whether pediatric otitis media is associated with the risk of asthma using the Korean National Health Insurance Service National Sample Cohort (NHIS-NSC 2002-2013) data. Subjects and Method In using the NHIS-NSC 2002-2013 data, children diagnosed as otitis media or bronchial asthma in 2002 were excluded from children from 1 to 8 years old in 2003. The patients who were diagnosed and treated as otitis media (n=8506) and the comparison group (n=65886) were enrolled in 2003. During a 10-year follow-up period until December 2013, the incidence of asthma between two groups was analyzed and the result was adjusted for the impact of comorbidities such as atopic dermatitis, allergic rhinitis with multivariate linear regression analyses. Results In 2003, 20.88% of first-year-old children were treated with otitis media. The prevalence of otitis media was maintained at 15% until age 4 and decreased rapidly after 5 years of age. Asthma incidence was reported higher in patients with otitis media compared to the comparison group, with an adjusted odds ratio of 1.196 [95% confidence interval (CI) 1.127-1.269] followed by patients with atopic dermatitis [hazard ratio (HR) 1.261, 95% CI 1.196-1.33], allergic rhinitis (HR 1.473, 95% CI 1.409-1.54). Conclusion Pediatric otitis media appeared to be associated with an increased risk of developing bronchial asthma after adjusting for other risk factors. Korean J Otorhinolaryngol-Head Neck Surg 2017;60(10):497-503

#Asthma #Dermatitis #atopic #Otitis media #Rhinitis #allergic.

참고문헌 (21)

참고문헌 신청

Alles R / 2001 / The prevalence of atopic disorders in children with chronic otitis media with effusion / Pediatr Allergy Immunol 12 (2) : 102 ~ 106

Eldeirawi K / 2010 / Frequent ear infections in infancy and the risk of asthma in Mexican American children / J Asthma 47 (4) : 473 ~ 477

Heinrich J / 2004 / Air pollution and otitis media: a review of evidence from epidemiologic studies / Curr Allergy Asthma Rep 4 (4) : 302 ~ 309

Holt PG / 2012 / Virus infection and allergy in the development of asthma: what is the connection? / Curr Opin Allergy Clin Immunol 12 (2) : 151 ~ 157

Hurst DS / 2011 / The role of allergy in otitis media with effusion / Otolaryngol Clin North Am 44 (3) : 637 ~ 654

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