Rate of Isolation and Trends of Antimicrobial  Resistance of Multidrug Resistant Pseudomonas  Aeruginosa from Otorrhea in Chronic Suppurative  Otitis Media

이선규; 박동춘; 김명구; 부성현; 최영준; 변재용; 박문서; 여승근

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자료유형: 학술저널

저자정보: 이선규 박동춘 김명구 부성현 최영준 변재용 박문서 여승근

저널정보: 대한이비인후과학회 Clinical and Experimental Otorhinolaryngology Clinical and Experimental Otorhinolaryngology 제5권 제1호

발행연도: 2012.1

수록면: 17 - 22 (6page)

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Objectives. To assess the rate of isolation of Pseudomonas aeruginosa (PA) and multidrug-resistant PA (MDR-PA) from patients with chronic suppurative otitis media (CSOM) otorrhea and the annual trend of antibiotic-resistance. Methods. Otorrhea samples were collected aseptically from 1,598 CSOM patients. The rate of bacterial isolation and the results of antibiotic susceptibility testing were evaluated retrospectively. Results. The PA isolation rate from CSOM otorrhea was 24.4%. Of the 398 isolated strains tested for their susceptibilities to 10 antibiotics, 395 strains showed definitive results. Of these, 183 (46.3%) were susceptible to whole antibiotics and 212 (53.7%) was resistant to more than 1 antibiotics, with the frequency of antibiotics-resistance increasing significantly over time. Although strains susceptible to all antibiotics decreased over time, the rate of isolation of MDRPA did not change significantly. Resistance to aminoglycosides and quinolones was higher than to other antibiotics and significantly increased over time, whereas resistance to other antibiotics showed no trend. Conclusion. MDR-PA, assessed using five individual antibiotics and six antibiotic-classes, showed no tendency to increase or decrease over time. This may have been due to increased concern about antibiotic-resistant bacterial strains, leading to improved infection control within hospitals and healthcare centers.

#Pseudomonas aeruginosa #Multidrug resistant #Chronic suppurative otitis media

참고문헌 (21)

참고문헌 신청

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