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민경근; 윤진호; 정주현; 임채영; 강일규; 김선태

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자료유형: 학술저널

저자정보: 민경근 윤진호 정주현 임채영 강일규 김선태

저널정보: 대한이비인후과학회 대한이비인후-두경부외과학회지 대한이비인후과학회지 두경부외과학 제51권 제7호

발행연도: 2008.1

수록면: 623 - 629 (7page)

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연구주제

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연구배경

🔬

연구방법

🏆

연구결과

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There are some difficulties and dilemmas in treating patients who show acute recurrent infection or persistent inflammation after sinus surgery. Recently, nebulized antibiotic therapy was recommended as another treatment option for these patients. Our study was to evaluate the effect of nebulized antibiotic therapy in these patients. Subjects and Method： We selected 38 adult patients who had received endoscopic surgery previously. They were patients of the refractory group who have showed persistent purulent rhinorrhea despite treatment for 2 months after sinus surgery and the acute exacerbation group who have showed repeated worsening of their symptoms more than 3 times for 6 months. Cultures were taken from all cases and proper oral antibiotics were used based on their culture results. Oral antibiotics were stopped during the nebulized antimicrobial therapy. Nebulized antibiotics therapy was performed 5 times a week for 4 weeks with cefmenoxime hydrochloride using ultrasonic nebulizer. The symptom score and endoscopic appearance were checked also before and 1, 2 and 3 months after the treatment. Results： In 38 patients, 6 patients were excluded due to follow up loss or voluntary stop of treatment and 32 patients were available. S. aureus, P. aeruginosa and coagulase-negative Staphylococcus were most common organisms in all patients. The symptom score and endoscopic appearance after the treatment showed significant improvement. No complication was found in all cases. Conclusion： Nebulized antibiotic therapy might be considered as another therapeutic option for patients with refractory or acute exacerbation of chronic rhinosinusitis after endoscopic sinus surgery. (Korean J Otorhinolaryngol-Head Neck Surg 2008;51:623-9)

#Sinus surgery·Infection·Nebulizer antibiotics.

참고문헌 (16)

참고문헌 신청

Brook I / 2001 / Correlation between microbiology and previous sinus surgery in patients with chronic maxillary sinusitis / Ann Otol Rhinol Laryngol 110 (2) : 148 ~ 151

Conrad DJ / 2003 / The clinical use of aerosolized antibiotics / Clin Pulm Med 10 : 201 ~ 207

Desrosiers MY / 2001 / Treatment of chronic rhinosinusitis refractory to other treatments with topical antibiotic therapy delivered by means of a large-particle nebulizer: R

Goh YH / 2000 / Current status of topical nasal antimicrobial agents / Laryngoscope 110 (6) : 875 ~ 880

Jee BH / 1999 / Isolated bacteria and their susceptibility to antibiotics in chronic sinusitis: Results of endoscopically guided cultures of maxillary sinus secretions / J R

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