국민건강보험공단 표본 코호트 자료를 이용한 돌발성 난청과 뇌졸중 연관성 분석

남재성; 정세원; 한수진; 장정현; 최현승

추천

검색

자료유형: 학술저널

저자정보: 남재성 정세원 한수진 장정현 최현승

저널정보: 대한이비인후과학회 대한이비인후-두경부외과학회지 대한이비인후과학회지 두경부외과학 제59권 제5호

발행연도: 2016.1

수록면: 353 - 360 (8page)

이용수

📌

연구주제

📖

연구배경

🔬

연구방법

🏆

연구결과

초록· 키워드

오류제보하기

Background and Objectives Sudden sensorineural hearing loss (S-SNHL) occurs abruptly, developing rapidly within 3 days. The criteria for the diagnosis of S-SNHL are idiopathic hearing loss of at least 30 dB over at least three serial test frequencies. This study estimated whether S-SNHL increases the risk of stroke using Korean National Health Insurance Service National Sample Cohort (NHIS-NSC 2002-2013) data. Subjects and Method Among NHIS-NSC 2002-2013, we excluded the patients diagnosed as S-SNHL or stroke in 2002. The patients who were diagnosed and treated as S-SNHL (n=2510) and the comparison group (n=12550) extracted using propensity score matching were enrolled. During an 11-year follow-up period until December 2013, the incidence of stroke among two groups was analyzed and the result was adjusted for the impact of comorbidities such as hypertension, diabetes, and chronic kidney disease with Cox proportional hazard regression. Results According to our data, 10.8% of S-SNHL patients (among 2510) and 7.8% of the comparison group (among 12550) had strokes. Stroke incidence was reported higher in patients with history of S-SNHL compared to the comparison group [hazard (HR), 1.15; 95% confidence interval (CI), 1.01-1.32] followed by patients with hypertension (HR, 2.51; 95% CI, 2.22-2.84), diabetes mellitus (HR, 1.62; 95% CI, 1.43-1.85). In terms of the type of strokes, S-SNHL increased the risk of ischemic stroke (HR, 1.18; 95% CI, 1.02-1.37). Conclusion S-SNHL appeared to be associated with an increased risk of developing stroke after adjusting for other risk factors. Korean J Otorhinolaryngol-Head Neck Surg 2016;59(5):353-60

#Brain ischemia ㆍIntracranial hemorrhages ㆍStroke ㆍSudden hearing loss.

참고문헌 (21)

참고문헌 신청

Wilson WR / 1980 / The efficacy of steroids in the treatment of idiopathic sudden hearing loss. A double-blind clinical study / Arch Otolaryngol 106(12):772~776

Burton MJ / 2008 / Scott-Brown’s Otolaryngology Head and Neck Surgery / Hodder Arnold :3577~3593

Patzak MJ / 2005 / Sudden hearing loss as the leading symptom of an infarction of the left anterior inferior cerebellar artery / HNO 53(9):797~799

Lee H / 2012 / Audiovestibular loss in anterior inferior cerebellar artery territory infarction: a window to early detection? / J Neurol Sci 313(1-2):153~159

Kim JD / 2014 / National Health Insurance Statistical Yearbook / Health Insurance Review and Assessment Service and National Health Insurance Service

함께 읽어보면 좋을 논문

논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!