소아에서 Methicillin-Resistant Staphylococcus Aureus(MRSA) 이루에 대한 치료분석

김창국; 나애선; 조용범; 이준규; 김승현

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자료유형: 학술저널

저자정보: 김창국 나애선 조용범 이준규 김승현

저널정보: 대한이비인후과학회 대한이비인후-두경부외과학회지 대한이비인후과학회지 두경부외과학 제46권 제1호

발행연도: 2003.1

수록면: 16 - 20 (5page)

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Background and Objectives：Recently, incidence of community-acquired methicilin-resistant Staphylococcus aureus (MRSA) infection has been increasing. There are problems with children with MRSA otorrhea in visiting otolaryngology clinics, since higher. In this study, we used the conventional antibiotics orally and topically for the treatment of otorrhea by MRSA infection to compare the therapeutic effects of conventional antibiotics with the systemic vancomycin or teicoplanin. The author also tried to determine the timing of systemic vancomycin injection for the control of MRSA otorrhea. Materials and Method：Twenty-eight pediatric patients with MRSA otorrhea were treated with either conventional antibiotics (20 patients) topicaly and oraly or systemic vancomycin or teicoplanin injection (8 patients). The use of vancomycin or teicoplanin injection was indicated when otorrhea didnt stop despite of 3-4 weeks of conventional treatment and when refered from local clinics, and in case of chole-steatoma, when it came as a result of complication of midle ear disease. Results：The average therapeutic period for the con-ventionally treated group was 24.7 days. On the other hand, the average period was 12.3 days and 9.8 days for the systemic vancomycin and teicoplanin injection group, respectively. Conclusion：applied for the treatment of MRSA otorrhea in children, has advantages in relation to time and economy, although the average therapeutic period was longer than the treatment with systemic vancomycin or teicoplanin injection. The author suggests the usage of conventional antibiotics for 3 weks prior to the use of systemic vancomycin injection. (Korean J Otolaryngol 2003 ;46 :16-20)

#메티실린 내성·황색 포도상구균·지역사회 감염·소아·Vancomycin. #Methicillin resistance· Staphylococcus aureus· Comunity-acquired infections· Child· Vancomycin.

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