지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 1 - 11 (11page)
이용수
초록· 키워드
오류제보하기
Background: Teleosts represent unique features in the regulation of muscle development and growth, with a great deal of myogenic plasticity. Muscle actins are major components to compose muscle fibers, and they play essential roles in cellular mobility and other related functions. In order to understand isoform-dependent roles of muscle actins in the mud loach (Misgurnus mizolepis), this study was aimed to characterize gene structure and expression pattern of the three muscle actin isoforms (α-skeletal, α-cardiac, and α-smooth muscle actins) isolated from this benthic fish species.
Results: Mud loach α-actin isoforms (ACTA1, ACTC1, and ACTA2) were fairly conserved in their primary structures and shared a high-sequence identity one another. At genomic level also, all the three isoforms exhibited the same exon-intron organization pattern characterized by eight translated exons. However, in mRNA expression patterns, these three actin isoforms were found to display an apparent isoform-dependency in tissue distribution (i.e., ACTA1 in the skeletal muscles, ACTC1 in the heart, and ACTA2 in the intestines) and developmental regulation (i.e., increased expression of ACTA1 and ACTC1 with the progress of myogenesis, and the significant elevation of ACTA2 during organ development in early larvae).
Conclusion: Data from this study suggest that three muscle actin isoforms have undergone certain functional differentiation with regard to their roles in the development and adult musculature, in spite of high structural similarity. Genetic information on muscle actins obtained in this study could provide a useful base to extend our understanding on evolutionary diversification of the myogenic regulation in teleosts.
목차
등록된 정보가 없습니다.
참고문헌 (23)
참고문헌 신청
Alves-Costa F / 2015 / Characterization of α-actin isoforms in white and red skeletal muscle types of Leporinus macrocephalus(Characiformes, Anostomidae) / Annal Braz Acad S
Bertola LD / 2008 / Developmental expression of the alpha-skeletal actin gene / BMC Evol Biol 8 : 166 ~
Chong SW / 2009 / Myogenesis and molecules?insights from zebrafish Danio rerio / J Fish Biol 74 : 1693 ~ 1755
Fujimoto T / 2006 / Developmental stages and germ cell lineage of the loach(Misgurnus anguillicaudatus) / Zool Sci 23 : 977 ~ 989
Gap L / 2014 / Ontogenetic development in the morphology and behavior of loach(Misgurnus anguillicaudatus)during early life stages / Chin J Oceanol Limnol 32 : 973 ~ 981
Bertola LD / 2008 / Developmental expression of the alpha-skeletal actin gene / BMC Evol Biol 8 : 166 ~
Chong SW / 2009 / Myogenesis and molecules?insights from zebrafish Danio rerio / J Fish Biol 74 : 1693 ~ 1755
Fujimoto T / 2006 / Developmental stages and germ cell lineage of the loach(Misgurnus anguillicaudatus) / Zool Sci 23 : 977 ~ 989
Gap L / 2014 / Ontogenetic development in the morphology and behavior of loach(Misgurnus anguillicaudatus)during early life stages / Chin J Oceanol Limnol 32 : 973 ~ 981
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Promoter characteristics and developmental expression patterns of three alpha actin gene isoforms in mud loach (Misgurnus mizolepis)
한국수산과학회 양식분과 학술대회
2015 .10
-
Gene structure and expression characteristics of liver-expressed antimicrobial peptide-2 isoforms in mud loach (Misgurnus mizolepis, Cypriniformes)
Fisheries and Aquatic Sciences
2017 .01
-
Functional characterization of mlc2f-promoter and recapitulation of skeletal muscle development in transgenic mud loach (Misgurnus mizolepis)
한국수산과학회 양식분과 학술대회
2016 .05
-
Metabolite profiling of Mud loach (Misgurnus mizolepis) from different geographical origins
한국수산과학회 양식분과 학술대회
2022 .10
-
A Shewanella putrefaciens infection in cultured Mud Loach (Misgurnus mizolepis)
한국수산과학회 양식분과 학술대회
2015 .10
-
Characterization and expression profiles of aquaporins (AQPs) 1a and 3a in mud loach Misgurnus mizolepis after experimental challenges
Fisheries and Aquatic Sciences
2017 .01
-
Comparative review of muscle fiber characteristics between porcine skeletal muscles
한국축산학회지
2024 .03
-
Studies of Natural Small-Molecule Compounds Modulating the Aging of Muscle and Muscle Stem Cells
한국식품영양과학회 학술대회발표집
2021 .10
-
Meeting the meat: delineating the molecular machinery of muscle development
한국축산학회지
2016 .01
-
미꾸라지(Misgurnus mizolepis)의 Shewanella putrefaciens 감염증
수산해양교육연구
2017 .08
-
Effects of Different Feeding Frequency on the Growth, Feed Utilization and Body Composition of Juvenile Mud Loach Misgurnus mizolepis in Semi-RAS(Recirculating Aquaculture System)
수산해양교육연구
2022 .10
-
Isolation of Full-length Actin7-like Gene in Onion (Allium cepa)
한국원예학회 학술발표요지
2018 .10
-
Comparative genomics of mitochondrial DNA in members of the loach
한국수산과학회 양식분과 학술대회
2021 .04
-
Expression profiles of aquaporins (AQPs) 1a and 3a in mud loach Misgumus mizolepis after different stimulatory treatments
한국수산과학회 양식분과 학술대회
2016 .05
-
Overview of muscle metabolism, muscle fiber characteristics, and meat quality
Korean Journal of Agricultural Science
2018 .03
-
Molecular cloning of insulin-like growth factor 1 (IGF-1) from mud loach
한국수산과학회 양식분과 학술대회
2015 .10
-
Silver and Sport Product Development for Muscle Loss Prevention and Muscle Strengthening
한국식품영양과학회 학술대회발표집
2017 .10
-
A taxaonomical study on populations of Misgurnus mizolepis from Korea
한국수산과학회 양식분과 학술대회
2022 .10
-
GAPDH, β-actin and β2-microglobulin, as three common reference genes, are not reliable for gene expression studies in equine adipose- and marrow-derived mesenchymal stem cells
한국축산학회지
2015 .01
-
국내 실내외 양식방법에 따른 미꾸라지, Misgurnus mizolepis의 성장특성
한국수산과학회 양식분과 학술대회
2020 .07
이 논문의 저자 정보
최근 본 자료
댓글(0)
0