지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2004.1
- 수록면
- 117 - 128 (12page)
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초록· 키워드
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Objectives : To examine the effects of Gojineumja on white rats which deteriorated immunity caused by Methotrexate(MTX), first of all, MTX was fed to the rats once a day for 4 day.
Methods : After the immune response of the rats are deteriorated, dried extracts of Gojineumja(GJE) mixed in water was fed to the white rats once a day for 14days. The next conclusion was made by examining the rates of B-cells and T-cells of the peripheral blood and the changes in rates of CD4+ T-cells and CD8+ T-cells of the blood sampled from the spleen and peripheral region. Especially the count of CD3+ CD4+ T-cells of the peripheral blood and the count of CD3+ CD4+ T-cells of the spleen the count of CD4+/ CD8+ T-cell of the peripheral blood and the spleen proved the significant effect of increasing immune responses statistically.
Results :
① The following are the summary of the results.
② The percentage of B lymphocyte of peripheral blood was increased significantly in GJE group as compared with control group.
③ The percentage of CD3+ CD4+ T-cell of peripheral blood was increased significantly in GJE group as compared with control group.
④ The percentage of CD3+ CD8+ T-cell of peripheral blood was not different statistically.
⑤ The percentage of CD4+/ CD8+ T-cell of peripheral blood was increased significantly in GJE group as compared with control group.
⑥ The percentage of CD3+ CD4+ T-cell of spleen was increased significantly in GJE group as compared with control group.
⑦ The percentage of CD3+ CD8+ T-cell was not different statistically.
⑧ The percentage of CD4+ /CD8+ T-cell was not different statistically.
Conclusions : Gojineumja has an effect of increasing immune responses on white rats with deteriorated immunity caused by MTX.
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