지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한치주과학회 Journal of Periodontal & Implant Science Journal of Periodontal & Implant Science 제35권 제1호
- 발행연도
- 2005.1
- 수록면
- 21 - 30 (10page)
이용수
초록· 키워드
오류제보하기
Matrix metalloproteinases (MMPs) are a family of host-derived proteolytic enzymes and implicated in the remodeling and degradation of extracellular matrix under both physiological and pathological conditions. Connective tissue degradation in periodontal diseases is thought to be due to excessive MMP activities over their specific inhibitors. The effects of lipopolysaccharide (LPS) from Prevotella intermedia, one of the major putative pathogens of periodontitis, on the expression of mRNA for MMPs and tissue inhibitors of metalloproteinases (TIMPs) in human gingival and periodontal ligament fibroblasts were examined by reverse transcriptase-polymerase chain reaction (RT-PCR). The expression of mRNAs encoding MMP-1, -2, -3, -10, and -14 was increased in human gingival fibroblasts treated with P. intermedia LPS, whereas MMP-11 and TIMP-2 mRNA expression was decreased in these cells stimulated with LPS. P. intermedia LPS increased the MMP-1, -2, -10, -11, and -14 mRNA expression and decreased TIMP-1 and -2 mRNA expression in human periodontal ligament fibroblasts. These findings imply that P. intermedia LPS may play an important role in the connective tissue degradation in periodontitis.
목차
등록된 정보가 없습니다.
참고문헌 (30)
참고문헌 신청
/ / Expression of matrix metalloproteinase-2 and -9 during early human wound healing : 176 ~ 182
/ / Wound healing in ovariectomiced rats Effects of chemically modified tetracycline and estrogen on matrix metalloproteinases -8 and -13 and type I collagen expression : 28
/ 1965 / extraction with phenol-water and further applications of the procedure Methods in carbohydrate chemistry : 83 ~ 91
/ 1978 / A modification of the Lowry procedure to simplify protein determination in membrane and lipoprotein samples 87 : 206 ~ 210
/ 1979 / A study of the bacteria associated with advancing periodontitis in man 6 : 278 ~ 307
/ / Wound healing in ovariectomiced rats Effects of chemically modified tetracycline and estrogen on matrix metalloproteinases -8 and -13 and type I collagen expression : 28
/ 1965 / extraction with phenol-water and further applications of the procedure Methods in carbohydrate chemistry : 83 ~ 91
/ 1978 / A modification of the Lowry procedure to simplify protein determination in membrane and lipoprotein samples 87 : 206 ~ 210
/ 1979 / A study of the bacteria associated with advancing periodontitis in man 6 : 278 ~ 307
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
유방 암종에서의 금속단백질 효소 및 효소저해자의 발현
Annals of Surgical Treatment and Research
1998 .11
-
Correlation of expression and activity of matrix metalloproteinase-9 and -2 in human gingival cells of periodontitis patients
Journal of Periodontal & Implant Science
2013 .01
-
The influence of type 2 diabetes mellitus on the expression of inflammatory mediators and tissue inhibitor of metalloproteinases-2 in human chronic periodontitis
Journal of Periodontal & Implant Science
2011 .01
-
MMP and TIMP production in periodontal ligament fibroblasts stimulated by Prevotella nigrescens lipopolysaccharide
Restorative Dentistry and Endodontics
2005 .01
-
Identification and Characterization of Matrix Metalloproteinase-2 (MMP-2) and Tissue Inhibitor of Metalloproteinase-2 (TIMP-2) Expressed in primary Hamster Tracheal Surface Epithelial cells
대한약학회 학술대회
2000 .01
-
Preoperative Levels of Matrix Metalloproteinase-7 and -9 and Tissue Inhibitor of Matrix Metalloproteinase-1 Relation to Pathologic Parameters in Bladder Carcinoma Patients
Asian Pacific journal of cancer prevention : APJCP
2013 .01
-
담낭 샘암종에서 Matrix Metalloproteinase (MMP)-2, MMP-9, Tissue Inhibitor of Metalloproteinase (TIMP)-1, TIMP-2의 발현
Journal of Pathology and Translational Medicine
2003 .01
-
결장암 및 직장암 환자의 암조직과 정상 점막조직에서 Matrix Metalloproteinase(MMP)-2, -9과 Tissue Inhibitor of Metalloproteinase (TIMP)-1, -2 발현에 대한 연구
대한외과학회 학술대회 초록집
2004 .10
-
유방암종에서 MMp-2, MTI-MMP, TIMP-2 mRNA의 발현
Journal of Pathology and Translational Medicine
2003 .01
-
Roles of Matrix Metalloproteinases and Their Targets in Epileptogenesis and Seizures
Clinical Psychopharmacology and Neuroscience
2013 .01
-
비소세포폐암에서 Matrix Metalloproteinase(MMPs)-2, 9와 Tissue Inhibitor of Metalloproteinase(TIMPs)-1, 2의 발현과 생존율과의 관계
Tuberculosis and Respiratory Diseases
2002 .01
-
The expression of a nitric oxide derivative, tissue inhibitors of metalloproteinase-3, and tissue inhibitors of metalloproteinase-4 in chronic periodontitis with type 2 diabetes mellitus
Journal of Periodontal & Implant Science
2013 .01
-
치은섬유아세포의 MMP 발현에 대한 Nitric Oxide의 영향
Journal of Periodontal & Implant Science
2003 .01
-
Associations of matrix metalloproteinase (MMP)-8, MMP-9, and their inhibitor, tissue inhibitor of metalloproteinase-1, with obesity-related biomarkers in apparently healthy adolescent boys
Clinical and Experimental Pediatrics
2014 .01
-
췌장관샘암종에서 Matrix Metalloproteinase-2 (MMP-2)와 Tissue Inhibitor of Metalloproteinase-2 (TIMP-2)의 발현
Journal of Pathology and Translational Medicine
2004 .01
-
Expression of collagenases (matrix metalloproteinase-1, 8, 13) and tissue inhibitor of metalloproteinase-1 of retrodiscal tissue in temporomandibular joint disorder patients
대한구강악안면외과학회지
2018 .01
-
Vitamin D Inhibits Expression and Activity of Matrix Metalloproteinase in Human Lung Fibroblasts (HFL-1) Cells
Tuberculosis and Respiratory Diseases
2014 .01
-
Roles of Matrix Metalloproteinase-9 in Cancer Metastasis
대한의생명과학회지
2014 .09
-
N-Acetylcysteine Prevents LPS-Induced Pro-inflammatory Cytokines and MMP2 Production in Gingival Fibroblasts
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2007 .01
-
Changes of Matrix Metalloproteinase and Tissue Inhibitors of Metalloproteinase in Patients with Rotator Cuff Tears
대한견주관절의학회 학술대회논문집
2009 .05
이 논문의 저자 정보
최근 본 자료
댓글(0)
0