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논문 기본 정보

자료유형
학술저널
저자정보
Gunes, Mustafa (Department of Urology, Yuzuncu Yil University Medical Faculty) Kemik, Ahu Serap (Department of Biochemistry, Cerrahpasa Medical Faculty, University of Istanbul) Pirincci, Necip (Department of Urology, Yuzuncu Yil University Medical Faculty) Gecit, Ilhan (Department of Urology, Yuzuncu Yil University Medical Faculty) Taken, Kerem (Urology Clinic of Van State Hospital) Yuksel, Mehmet Bilgehan (Department of Urology, Celal Bayar University Medical Faculty) Kaba, Mehmet (Urology Clinic of Van State Hospital) Eryilmaz, Recep (Department of Urology, Yuzuncu Yil University Medical Faculty)
저널정보
아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP Asian Pacific journal of cancer prevention : APJCP 제14권 제2호
발행연도
2013.1
수록면
873 - 876 (4page)

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Our aim was to test the hypothesis that preoperative serum levels of matrix metalloproteinase-7 (MMP-7) and -9 (MMP-9) and tissue inhibitor of matrix metalloproteinase (TIMP-1) levels correlate with pathological features. Serum levels of MMP-7, and MMP-9 and TIMP-1 were determined in 90 bladder cancer patients and 40 healthy controls using an enzyme linked immunosorbent assay. Preoperative serum MMP-7 and MMP-9 levels were significantly higher in cancer patients than control groups (p<0.001). In contast, serum TIMP-1 levels were lower (p<0.001). Alteration in MMP-7, and MMP-9, and TIMP-1 production may contribute to tumor angiogenesis and be associated with clinic-pathological features.

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