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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 12 - 21 (10page)
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Abstract
Objectives To evaluate the effects of three acids on the microhardness of set mineral trioxide aggregate (MTA) and root dentin, and cytotoxicity on murine macrophage.
Materials and Methods OrthoMTA (BioMTA) was mixed and packed into the human root dentin blocks of 1.5 mm diameter and 5 mm height. Four groups, each of ten roots, were exposed to 10% citric acid (CA), 5% glycolic acid (GA), 17% ethylenediaminetetraacetic acid (EDTA), and saline for five minutes after setting of the OrthoMTA. Vickers surface microhardness of set MTA and dentin was measured before and after exposure to solutions, and compared between groups using one-way ANOVA with Tukey test. The microhardness value of each group was analyzed using student t test. Acid-treated OrthoMTA and dentin was examined by scanning electron microscope (SEM). Cell viability of tested solutions was assessed using WST-8 assay and murine macrophage.
Results Three test solutions reduced microhardness of dentin. 17% EDTA demonstrated severe dentinal erosion, significantly reduced the dentinal microhardness compared to 10% CA (p = 0.034) or 5% GA (p = 0.006). 10% CA or 5% GA significantly reduced the surface microhardness of set MTA compared to 17% EDTA and saline (p < 0.001). Acid-treated OrthoMTA demonstrated microporous structure with destruction of globular crystal. EDTA exhibited significantly more cellular toxicity than the other acidic solutions at diluted concentrations (0.2, 0.5, 1.0%).
Conclusions Tested acidic solutions reduced microhardness of root dentin. Five minute's application of 10% CA and 5% GA significantly reduced the microhardness of set OrthoMTA with lower cellular cytotoxicity compared to 17% EDTA.
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참고문헌 (38)
참고문헌 신청
Torabinejad M / 1993 / Sealing ability of a mineral trioxide aggregate when used as a root end filling material / J Endod 19:591~595
Camilleri J. / 2007 / Hydration mechanisms of mineral trioxide aggregate / Int Endod J 40:462~470
Torabinejad M / 2010 / Mineral trioxide aggregate:a comprehensive literature review-part II: leakage and biocompatibility investigations / J Endod 36:190~202
Li Z / 2015 / Direct pulp capping with calcium hydroxide or mineral trioxide aggregate: a meta-analysis / J Endod 41:1412~1417
Bogen G / 2009 / Mineral trioxide aggregate obturation: a review and case series / J Endod 35:777~790
Camilleri J. / 2007 / Hydration mechanisms of mineral trioxide aggregate / Int Endod J 40:462~470
Torabinejad M / 2010 / Mineral trioxide aggregate:a comprehensive literature review-part II: leakage and biocompatibility investigations / J Endod 36:190~202
Li Z / 2015 / Direct pulp capping with calcium hydroxide or mineral trioxide aggregate: a meta-analysis / J Endod 41:1412~1417
Bogen G / 2009 / Mineral trioxide aggregate obturation: a review and case series / J Endod 35:777~790
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