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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 443 - 445 (3page)
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Dear Editor, Almost all cases of CML show typical clinical features such as marked leukocytosis in the peripheral blood (PB), splenomegaly, and granulocytic hyperplasia in the PB and bone marrow (BM). CML without leukocytosis in the PB is rare but could occur if “undiagnosed” CML patients received cytoreductive therapy due to the patient’s predisposing hematologic malignancies. In contrast, the presence of the BCR-ABL1 mutation without the clinical features of CML and unrelated to cytoreductive therapy (so-called “preleukemic phase” or “smoldering” CML) is very rare [1-3]. Here, we report a rare case of hidden preleukemic phase of CML presenting without leukocytosis in the PB unrelated to prior chemotherapy in a diffuse large B cell lymphoma (DLBCL) patient. To our knowledge, this is the first case of preleukemic phase of CML in the Korean population.
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참고문헌 (3)
참고문헌 신청
Aye le L / 2016 / Preleukemic phase of chronic myelogenous leukemia: morphologic and immunohistochemical characterization of 7 cases / Ann Diagn Pathol 21 : 53 ~ 58
Bennett JM / 2014 / Preleukemic or smoldering chronic myelogenous leukemia (CML): BCR-ABL1 positive: A brief case report / Leuk Res Rep 4 : 12 ~ 14
Hudnall SD / 2007 / Prolonged preleukemic phase of chronic myelogenous leukemia / Exp Mol Pathol 83 : 484 ~ 489
Bennett JM / 2014 / Preleukemic or smoldering chronic myelogenous leukemia (CML): BCR-ABL1 positive: A brief case report / Leuk Res Rep 4 : 12 ~ 14
Hudnall SD / 2007 / Prolonged preleukemic phase of chronic myelogenous leukemia / Exp Mol Pathol 83 : 484 ~ 489
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