지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
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Objectives: Approximately 10% to 15% of lung cancer cases occur in never-smokers. Hormonal factors have been suggested to lead to an elevated risk of lung cancer in women. This systematic review (SR) aimed to investigate the association between hormonal replacement therapy (HRT) and the risk of lung cancer in women using cohort studies.
Methods: We first obtained previous SR articles on this topic. Based on these studies we made a list of refereed, cited, and related articles using the PubMed and Scopus databases. All cohort studies that evaluated the relative risk of HRT exposure on lung cancer occurrence in women were selected. Estimate of summary effect size (sES) with 95% confidence intervals (CIs) were calculated.
Results: A total of 14 cohort studies were finally selected. A random effect model was applied due to heterogeneity (I-squared, 64.3%). The sES of the 14 articles evaluating the impact of HRT exposure on lung cancer occurrence in women indicated no statistically significant increase in lung cancer risk (sES, 0.99; 95% CI, 0.90 to 1.09).
Conclusions: These results showed that HRT history had no effect on the risk of lung cancer in women, even though the sES of case-control studies described in previous SR articles indicated that HRT had a protective effect against lung cancer. It is necessary to conduct a pooled analysis of cohort studies.
목차
등록된 정보가 없습니다.
참고문헌 (25)
참고문헌 신청
Adami HO / 1989 / Risk of cancer in women receiving hormone replacement therapy / Int J Cancer 44 (5) : 833 ~ 839
Alberg AJ / 2013 / Invited commentary: the etiology of lung cancer in men compared with women / Am J Epidemiol 177 (7) : 613 ~ 616
Bae JM / 2014 / Narrative reviews / Epidemiol Health 36 : e2014018 ~
Bae JM / 2015 / Human papillomavirus 16 infection as a potential risk factor for prostate cancer: an adaptive meta-analysis / Epidemiol Health 37 : e2015005 ~
Bae JM / 2015 / The necessity of an observational study on the interactions between allergic history and citrus fruit intake for the prevention of pancreatic cancer / Epidem
Alberg AJ / 2013 / Invited commentary: the etiology of lung cancer in men compared with women / Am J Epidemiol 177 (7) : 613 ~ 616
Bae JM / 2014 / Narrative reviews / Epidemiol Health 36 : e2014018 ~
Bae JM / 2015 / Human papillomavirus 16 infection as a potential risk factor for prostate cancer: an adaptive meta-analysis / Epidemiol Health 37 : e2015005 ~
Bae JM / 2015 / The necessity of an observational study on the interactions between allergic history and citrus fruit intake for the prevention of pancreatic cancer / Epidem
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