지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 748 - 756 (9page)
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초록· 키워드
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Purpose Because of growing concerns about lung cancer in female never smokers, chest low-dose computed tomography (LDCT) screening is often performed although it has never shown clinical benefits. We examine whether or not female never smokers really need annual LDCT screening when the initial LDCT showed negative findings. Materials and Methods This retrospective cohort study included 4,365 female never smokers aged 40 to 79 years who performed initial LDCT from Aug 2002 to Dec 2007. Lung cancer diagnosis was identified from the Korea Central Cancer Registry Database registered until December 31, 2013. We calculated the incidence, cumulative probability, and standardized incidence ratio (SIR) of lung cancer by Lung Imaging Reporting and Data System (Lung-RADS) categories showed on initial LDCT. Results After median follow-up of 9.69 years, 22 (0.5%) had lung cancer. Lung cancer incidence for Lung-RADS category 4 was 1,848.4 (95% confidence interval [CI], 1,132.4 to 3,017.2) per 100,000 person-years and 16.4 (95% CI, 7.4 to 36.4) for categories 1, 2, and 3 combined. The cumulative probability of lung cancer for category 4 was 10.6% at 5 years and 14.8% at 10 years while they were 0.07% and 0.17% when categories 1, 2, and 3 were combined. The SIR for subjects with category 4 was 43.80 (95% CI, 25.03 to 71.14), which was much higher than 0.47 (95% CI, 0.17 to 1.02) for categories 1, 2, and 3 combined. Conclusion Considering the low risk of lung cancer development in female never smokers, it seems unnecessary to repeat annual LDCT screening for at least 5 years or even longer unless the initial LDCT showed Lung-RADS category 4 findings.
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등록된 정보가 없습니다.
참고문헌 (30)
참고문헌 신청
National Lung Screening Trial Research Team / 2011 / Reduced lung-cancer mortality with low-dose computed tomographic screening / N Engl J Med 365:395~409
Moyer VA / 2014 / Screening for lung cancer: U.S. Preventive Services Task Force recommendation statement / Ann Intern Med 160:330~338
Nawa T / 2012 / Long-term prognosis of patients with lung cancer detected on low-dose chest computed tomography screening / Lung Cancer 75:197~202
Yi CA / 2015 / Low-dose CT screening in an Asian population with diverse risk for lung cancer: a retrospective cohort study / Eur Radiol 25:2335~2345
International Early Lung Cancer Action Program Investigators / 2006 / Survival of patients with stage I lung cancer detected on CT screening / N Engl J Med 355:1763~1771
Moyer VA / 2014 / Screening for lung cancer: U.S. Preventive Services Task Force recommendation statement / Ann Intern Med 160:330~338
Nawa T / 2012 / Long-term prognosis of patients with lung cancer detected on low-dose chest computed tomography screening / Lung Cancer 75:197~202
Yi CA / 2015 / Low-dose CT screening in an Asian population with diverse risk for lung cancer: a retrospective cohort study / Eur Radiol 25:2335~2345
International Early Lung Cancer Action Program Investigators / 2006 / Survival of patients with stage I lung cancer detected on CT screening / N Engl J Med 355:1763~1771
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