Short-term Effect of Fine Particulate Matter on Children's Hospital Admissions and Emergency Department Visits for Asthma: A Systematic Review and Meta-analysis

임형렬; 권호장; 임지애; 최종혁; 하미나; 황승식; 최원준

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자료유형: 학술저널

저자정보: 임형렬 권호장 임지애 최종혁 하미나 황승식 최원준

저널정보: 대한예방의학회 예방의학회지 예방의학회지 제49권 제4호

발행연도: 2016.1

수록면: 205 - 219 (15page)

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Objectives: No children-specified review and meta-analysis paper about the short-term effect of fine particulate matter (PM2.5) on hospital admissions and emergency department visits for asthma has been published. We calculated more precise pooled effect estimates on this topic and evaluated the variation in effect size according to the differences in study characteristics not considered in previous studies. Methods: Two authors each independently searched PubMed and EMBASE for relevant studies in March, 2016. We conducted random effect meta-analyses and mixed-effect meta-regression analyses using retrieved summary effect estimates and 95% confidence intervals (CIs) and some characteristics of selected studies. The Egger’s test and funnel plot were used to check publication bias. All analyses were done using R version 3.1.3. Results: We ultimately retrieved 26 time-series and case-crossover design studies about the short-term effect of PM2.5 on children’s hospital admissions and emergency department visits for asthma. In the primary meta-analysis, children’s hospital admissions and emergency department visits for asthma were positively associated with a short-term 10 μg/m3 increase in PM2.5 (relative risk, 1.048; 95% CI, 1.028 to 1.067; I2=95.7%). We also found different effect coefficients by region; the value in Asia was estimated to be lower than in North America or Europe. Conclusions: We strengthened the evidence on the short-term effect of PM2.5 on children’s hospital admissions and emergency department visits for asthma. Further studies from other regions outside North America and Europe regions are needed for more generalizable evidence.

#Particulate matter #Asthma #Child #Review #Meta-analysis #Hospitalization

참고문헌 (53)

참고문헌 신청

Vallero DA / 2014 / Fundamentals of air pollution / Academic Press :48

Pope CA / 2009 / Cardiovascular mortality and exposure to airborne fine particulate matter and cigarette smoke: shape of the exposure-response relationship / Circulation 120(11):941~948

Lepeule J / 2012 / Chronic exposure to fine particles and mortality: an extended follow-up of the Harvard Six Cities study from 1974 to 2009 / Environ Health Perspect 120(7):965~970

Kwon HJ / 2011 / Epidemiologic study of allergic diseases in Korean children :23~24

Zheng XY / 2015 / Association between air pollutants and asthma emergency room visits and hospital admissions in time series studies: a systematic review and meta-analysis / PLoS One 10(9):e0138146

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