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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2003.1
- 수록면
- 177 - 180 (4page)
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초록· 키워드
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Among patients with lung cancer, approximately 15%
have small cell lung cancer (SCLC), SCLC is usually
staged as either limited and extensive. Extensive-stage
SCLC is treated primarily with chemotherapy. A recent
Japanese randomized trial compared cisplatin and irinotecan
(IP) with cisplatin and etoposide (EP). Patients in
the IP arm did significantly better than patients in the EP
arm. In the IP arm, the response rate was 84%, and the
median overall survival period was 12.8 months. Limitedstage
SCLC is usually treated with concurrent chemotherapy
and accelerated radiation therapy, and approximately
20% of patients are cured. Future research should focus
on optimizing chemotherapy regimens and radiation therapy
schedules. The role of molecular targeted drugs in
the treatment of SCLC must also be evaluated. (Cancer Res Treat. 2003;35:177-180)
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