지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 575 - 581 (7page)
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Purpose The purpose of this study was to evaluate the clinical features and the long-term outcomes of primary conjunctival marginal zone B-cell lymphoma (MZBCL) patients who were treated with radiation therapy (RT). Materials and Methods Retrospective data of 79 patients with 121 primary conjunctival MZBCL lesions were collected from January 1, 2001 till June 30, 2014. All lesions were treated by local RT (26 Gy) with patient-specific customized lens-shielding device. Results The current Korean patients’ cohort showed younger median age at diagnosis (38 years), great female preponderance (78.5%) and more frequent bilateral involvement (53.2%) than the previous studies. Following 26 Gy’s RT, excellent clinical outcomes were achieved: 5-year rates of overall survival, local relapse-free survival, and contralateral relapse-free survival were 100%, 98.1%, and 91.5%, respectively. Two patients (2.5%) developed local relapse and five (6.3%) developed relapse at initially uninvolved contralateral conjunctiva with median interval of 52.9 months, and late adverse events of grade 2 and 3 occurred in seven (8.8%) and two (2.5%) patients, respectively. Conclusion 26 Gy’s RT was highly effective and safe, with the use of lens-shielding device, in treating patients with primary conjunctival MZBCL.
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참고문헌 (24)
참고문헌 신청
Kirkegaard MM / 2015 / Malignant lymphoma of the conjunctiva / Surv Ophthalmol 60:444~458
Kirkegaard MM / 2016 / Conjunctival lymphoma: an international multicenter retrospective study / JAMA Ophthalmol 134:406~414
Matsuo T / 2007 / Spontaneous regression of bilateral conjunctival extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue / J Clin Exp Hematop 47:79~81
Tanimoto K / 2006 / Long-term follow-up results of no initial therapy for ocular adnexal MALT lymphoma / Ann Oncol 17:135~140
Han JJ / 2015 / Long-term outcomes of first-line treatment with doxycycline in patients with previously untreated ocular adnexal marginal zone B cell lymphoma / Ann Hematol 94:575~581
Kirkegaard MM / 2016 / Conjunctival lymphoma: an international multicenter retrospective study / JAMA Ophthalmol 134:406~414
Matsuo T / 2007 / Spontaneous regression of bilateral conjunctival extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue / J Clin Exp Hematop 47:79~81
Tanimoto K / 2006 / Long-term follow-up results of no initial therapy for ocular adnexal MALT lymphoma / Ann Oncol 17:135~140
Han JJ / 2015 / Long-term outcomes of first-line treatment with doxycycline in patients with previously untreated ocular adnexal marginal zone B cell lymphoma / Ann Hematol 94:575~581
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